The effects of age on the severity of joint damage and intra-articular inflammation following a simulated medial meniscus injury in 3, 6, and 9 month old male rats.

Conclusions: These data indicate the severity of cartilage damage subsequent to MCLT+MMT surgery is related to the rat's age at the time of injury. However, despite greater levels of cartilage damage, the level of intra-articular inflammation was not necessarily affected in 3, 6, and 9 month old male rats. PMID: 31438735 [PubMed - as supplied by publisher]
Source: Connective Tissue Research - Category: Research Tags: Connect Tissue Res Source Type: research

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aacute;č P Abstract The team of authors presents a case of the patient who suffered an isolated unstable extra-articular distal ulnar fracture, the surgical treatment of which was affected by a postponed management in consequence of inadequate primary treatment. The primary non-operative treatment resulted in a complex malunion ad latus, ad axim and ad peripheriam. The malunion which led to a painful restricted range of motion of the forearm (59%), decreased hand grip strength and significant limitation of activities of daily living was surgically treated by a triplane corrective osteotomy at 11 months after inju...
Source: Acta Orthopaedica - Category: Orthopaedics Authors: Tags: Acta Chir Orthop Traumatol Cech Source Type: research
The number of total knee arthroplasty (TKA) procedures performed in the United States has been increasing. Increased complication rates have been demonstrated in patients with post-traumatic arthritis (PTA) undergoing TKA. However, there remains limited data directly comparing outcomes of TKA performed for osteoarthritis (OA) and PTA.
Source: The Journal of Arthroplasty - Category: Orthopaedics Authors: Source Type: research
Discussion/conclusionThe study hypothesis was confirmed: there were no differences according to primary versus secondary osteoarthritis in preoperative profile or results. Elbow osteoarthritis entails mechanical impingement. Arthroscopic debridement gave good results independently of primary or post-traumatic etiology.Level of evidenceIII, prospective comparative observational multicenter cohort study.
Source: Orthopaedics and Traumatology: Surgery and Research - Category: Orthopaedics Source Type: research
Deleterious impact loading to cartilage initiates post-traumatic osteoarthritis (OA). While cytokine and enzyme levels regulate disease progression, specific mechanical cues that elucidate cellular OA origins merit further investigation. We defined the dominant pericellular and cellular strain/stress transfer mechanisms following bulk-tissue injury associated with cell death.
Source: Osteoarthritis and Cartilage - Category: Rheumatology Authors: Source Type: research
Conditions:   Osteoarthritis, Hip;   Rheumatoid Arthritis;   Fracture of Hip;   Dislocated Hip;   Osteonecrosis;   Post-traumatic; Arthrosis;   Subluxation Hip Intervention:   Device: Patients who met the inclusion/exclusion criteria to receive the Avenir Müller stem. Sponsor:   Zimmer Biomet Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Osteoarthritis, Hip;   Fracture of Hip;   Avascular Necrosis of Hip;   Dislocated Hip;   Osteonecrosis;   Post-traumatic; Arthrosis;   Rheumatoid Arthritis;   Subluxation Hip Intervention:   Device: Patients who received the Stafit Acetabular System Sponsor:   Zimmer Biomet Terminated
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Osteoarthritis, Hip;   Rheumatoid Arthritis;   Fracture of Hip;   Dislocated Hip;   Osteonecrosis;   Post-traumatic; Arthrosis;   Subluxation Hip Intervention:   Device: Patients who met the inclusion/exclusion criteria to receive the Avenir Müller stem. Sponsor:   Zimmer Biomet Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Osteoarthritis, Hip;   Fracture of Hip;   Avascular Necrosis of Hip;   Dislocated Hip;   Osteonecrosis;   Post-traumatic; Arthrosis;   Rheumatoid Arthritis;   Subluxation Hip Intervention:   Device: Patients who received the Stafit Acetabular System Sponsor:   Zimmer Biomet Terminated
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Osteoarthritis, Hip;   Rheumatoid Arthritis;   Fracture of Hip;   Dislocated Hip;   Osteonecrosis;   Post-traumatic; Arthrosis;   Subluxation Hip Intervention:   Device: Patients who met the inclusion/exclusion criteria to receive the Avenir Müller stem. Sponsor:   Zimmer Biomet Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Osteoarthritis, Hip;   Fracture of Hip;   Avascular Necrosis of Hip;   Dislocated Hip;   Osteonecrosis;   Post-traumatic; Arthrosis;   Rheumatoid Arthritis;   Subluxation Hip Intervention:   Device: Patients who received the Stafit Acetabular System Sponsor:   Zimmer Biomet Terminated
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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