Sensors, Vol. 19, Pages 3683: A Barcoded Polymer-Based Cross-Reactive Spectroscopic Sensor Array for Organic Volatiles

Sensors, Vol. 19, Pages 3683: A Barcoded Polymer-Based Cross-Reactive Spectroscopic Sensor Array for Organic Volatiles
Sensors doi: 10.3390/s19173683
Authors:
Jessica E. Fitzgerald
Jianliang Shen
Hicham Fenniri

The development of cross-reactive sensor arrays for volatile organics (electronic noses, e-noses) is an active area of research. In this manuscript, we present a new format for barcoded polymer sensor arrays based on porous polymer beads. An array of nine self-encoded polymers was analyzed by Raman spectroscopy before and after exposure to a series of volatile organic compounds, and the changes in the vibrational fingerprints of their polymers was recorded before and after exposure. Our results show that the spectroscopic changes experienced by the porous spectroscopically encoded beads after exposure to an analyte can be used to identify and classify the target analytes. To expedite this analysis, analyte-specific changes induced in the sensor arrays were transformed into a response pattern using multivariate data analysis. These studies established the barcoded bead array format as a potentially effective sensing element in e-nose devices. Devices such as these have the potential to advance personalized medicine, providing a platform for non-invasive, real-time volatile metabolite detection.

Source: Sensors - August 23, 2019 Category: Biotechnology Authors: Jessica E. Fitzgerald Jianliang Shen Hicham Fenniri Tags: Article Source Type: research