The important role of central sensitization in chronic musculoskeletal pain seen in different rheumatic diseases
This study explored the role of central sensitization (CS) pain in patients with various rheumatic diseases using the CS inventory (CSI).MethodsA total of 193 patients of mean age 50.72 ± 9.65 years were included; they were divided into four different groups in terms of their rheumatic diseases. Patients with rheumatoid arthritis (RA), spondyloarthropathy (SpA), osteoarthritis (OA), and fibromyalgia syndrome (FMS) were evaluated in tertiary care rheumatology/pain medicine se ttings. Disease duration and activity, the Bath Ankylosing Spondylitis Disease Activity Index, the Disease Activity Score-28, and pain severity (evaluated using a visual analog scale) were assessed, and the Turkish version of the CSI administered.ResultsCS syndromes were present in almost half the patients (45% of SpA, 41% of RA, 62% of OA, and 94% of FMS patients). We found no significant relationship between disease activity and the CSI-A scores in SpA or RA patients (p = 0.731 andp = 0.390, respectively). As expected, the CSI-A scores were highest in the FMS group (p = 0.000), but were similar in the other groups (p
This study aimed to compare serum levels of vascular endothelial growth factor (VEGF) and the VEGF receptors, VEGFR-1 and VEGFR-2, free placental growth factor (fPGF), endostatin, and serum pregnancy-associated plasma protein-A (PAPP-A) levels in women with mild and severe preeclampsia and healthy pregnant women. MATERIAL AND METHODS A included patients diagnosed with mild preeclampsia (n=32), severe preeclampsia (n=32), and healthy pregnant women (n=24). Serum levels of VEGF-A, VEGFR-1, VEGFR-2, fPGF, endostatin, and PAPP-A levels were measured by enzyme-linked immunosorbent assay (ELISA). RESULTS In women with mild and s...
Conclusion: The results indicated that ICU staff in Turkey had a high rate of burnout. PMID: 31522223 [PubMed - in process]
Authors: Alshahrani MS Abstract OBJECTIVES: To evaluate the attitudes of pregnant women towards different forms of labor pain relief, preferred methods of pain relief, and the effects of social media on their awareness and knowledge. METHODS: This was a cross-sectional study conducted between April and August 2017 in the Maternity and Children's Hospital, Najran, Saudi Arabia. A total of 416 pregnant women were interviewed and analyzed using IBM Sstatistical Package for Social Sciences version 20 (IBM Corp, Armonk, NY, USA). RESULTS: A total of 62.7% were aware of labor pain. However, 58.7% of the total sam...
CONCLUSION: This study demonstrated that the use of sugammadex results in less time to recovery and less agitation in comparison to conventional administration of neostigmine + atropine in the reversal of neuromuscular blocking after adenotonsillectomy. PMID: 31522218 [PubMed - in process]
Authors: Hao J, Dong B, Zhang J, Luo Z Abstract OBJECTIVES: To evaluate whether pre-emptive analgesia is an effective technique to reduce postoperative delirium (PD) in geriatric patients with hip fracture. METHODS: This is a double-blind randomized clinical trial. Ninety elderly patients scheduled for hipfracture surgery at HongHui Hospital, Xi'an Jiaotong University, Xi'an, China between March 2018 and January 2019 were divided into 2 groups. On arrival at the emergency department, the experimental group (n=44) received ultrasound-guided continuous fascia iliaca compartment block (...
Hi all, For those doing or have completed a pain fellowship, what is the best way to learn? Are there any great resources/textbooks/videos that are helpful? I am now about 1 month in and although the teaching is good at my program, I feel as though I haven't even touched the tip of the iceberg and am trying to figure out where to go from here. Any advice is greatly appreciated!
Conditions: Pain; Depressive Symptoms; Frailty; Aging Intervention: Behavioral: DAPPER Sponsors: Johns Hopkins University; Robert Wood Johnson Foundation; National Institute on Aging (NIA) Not yet recruiting
Conditions: Headache Disorders, Secondary; Post-Dural Puncture Headache; Migraine Disorders; Back Pain; Anesthesia Intervention: Sponsor: Stanford University Active, not recruiting
Condition: Endometriosis Intervention: Dietary Supplement: Meta19.01 Sponsor: Metagenics Europe Not yet recruiting
Conditions: Opioid-use Disorder; Opioid Use Disorder, Mild Interventions: Drug: Buprenorphine; Drug: Buprenorphine/naloxone Sponsor: Massachusetts General Hospital Not yet recruiting