Imaging Evaluation of Lung Transplantation Patients: A Time and Etiology-based Approach to High-resolution Computed Tomography Interpretation

Lung transplantation is an established therapeutic option for patients with irreversible end-stage pulmonary disease limiting life expectancy and quality of life. Common indications for lung transplantation include chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, cystic fibrosis, pulmonary arterial hypertension, and alpha-1 antitrypsin deficiency. Complications of lung transplantation can be broadly divided etiologically into surgical, infectious, immunologic, or neoplastic. Moreover, specific complications often occur within a certain time interval following surgery, which can be broadly classified as early (6 mo). Thus, each group of complications can further be categorized on the basis of the time continuum from transplantation. Imaging, primarily by high-resolution computed tomography, plays a critical role in early diagnosis of complications after lung transplantation. Early recognition of complications by the radiologist, and initiation of therapy, contributes to improved morbidity and mortality. However, accurate diagnosis is only feasible if one has a thorough understanding of the major etiologic categories of complications and how they relate to the time course since transplantation. We review imaging manifestations of lung transplant complications via a framework that includes the following major etiologic categories: surgical; infectious; immunologic; and neoplastic; and the following time frames: surgery to 6 weeks; 6 weeks to 6 months;...
Source: Journal of Thoracic Imaging - Category: Radiology Tags: Review Articles Source Type: research

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Source: Expert Review of Clinical Immunology - Category: Allergy & Immunology Tags: Expert Rev Clin Immunol Source Type: research
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Source: Expert Opinion on Investigational Drugs - Category: Drugs & Pharmacology Tags: Expert Opin Investig Drugs Source Type: research
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Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
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Source: Journal of Biosciences - Category: Biomedical Science Authors: Tags: J Biosci Source Type: research
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Source: Annals of Vascular Surgery - Category: Surgery Authors: Source Type: research
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Source: Hernia - Category: Sports Medicine Source Type: research
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Source: Annals of Coloproctology - Category: Gastroenterology Tags: Ann Coloproctol Source Type: research
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Source: Annals of Coloproctology - Category: Gastroenterology Tags: Ann Coloproctol Source Type: research
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Source: International Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
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Source: Archives of Plastic Surgery - Category: Cosmetic Surgery Tags: Arch Plast Surg Source Type: research
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