Absence of kelch13 artemisinin resistance markers but strong selection for lumefantrine-tolerance molecular markers following 18 years of artemisinin-based combination therapy use in Mpumalanga Province, South Africa (2001 –2018)

The ability of Plasmodium falciparum parasites to develop resistance to widely used anti-malarials threatens malaria control and elimination efforts. Regular drug efficacy monitoring is essential for ensuring eff...

Source: Malaria Journal - August 22, 2019 Category: Infectious Diseases Authors: Jaishree Raman, Frank M. Kagoro, Aaron Mabuza, Gillian Malatje, Anthony Reid, John Frean and Karen I. Barnes Tags: Research Source Type: research