Antibody Deficiency Testing for Primary Immune Deficiency - A Practical Review for the Clinician

A significant proportion of primary immunodeficiency (PID) diseases include humoral deficiency. Humoral deficiencies range in severity from complete deficiencies observed in diseases such as X-linked or autosomal recessive agammaglobulinemias and certain severe combined immune deficiencies (SCID), to milder specific antibody deficiencies. According to a recent update from the Jeffrey Modell Centers Network, disorders classified as primarily humoral deficiencies accounted for 45% of survey center PID patients worldwide, not including the many additional patients with combined immune deficiencies who also suffer from antibody deficiency.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: CME Reviews Source Type: research