Enhanced pulmonary uptake on 18 F-FES-PET/CT scans after irradiation of the thoracic area: related to fibrosis?

ConclusionAfter irradiation of the thorax, enhanced non-tumor uptake on FES-PET can be observed in the radiation field in a significant proportion of patients. This seems to be related to fibrosis. When observing enhanced FES uptake in the lungs, this should not be interpreted as metastases. Information on recent radiation therapy or history of pulmonary fibrosis should therefore be taken into consideration.
Source: EJNMMI Research - Category: Radiology Source Type: research