Evofosfamide sensitizes esophageal carcinomas to radiation without increasing normal tissue toxicity.

CONCLUSION: The combination of TH-302 and radiotherapy might be a promising approach to improve the therapeutic index for esophageal cancer patients.
PMID: 31431383 [PubMed - as supplied by publisher]

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - August 16, 2019 Category: Radiology Authors: Spiegelberg L, van Hoof SJ, Biemans R, Lieuwes NG, Marcus D, Niemans R, Theys J, Yaromina A, Lambin P, Verhaegen F, Dubois LJ Tags: Radiother Oncol Source Type: research