Safety and efficacy of reduced dose and margins to involved lymph node metastases in locally advanced NSCLC patients.
CONCLUSION: A reduction in PTV-margins and dose from 70 Gy to 60 Gy to the involved lymph nodes in LA-NSCLC patients receiving (chemo)radiotherapy did not result in an increase in regional failures. Moreover, significantly lower acute toxicities and an improved OS were observed in the reduction-cohort.
PMID: 31431389 [PubMed - as supplied by publisher]
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - Category: Radiology Authors: van Diessen JNA, Kwint M, Sonke JJ, Walraven I, Stam B, de Langen AJ, Knegjens J, Belderbos JSA Tags: Radiother Oncol Source Type: research
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