P32. Can CT-based bone mineral density predict proximal junctional fracture?

Proximal junctional fractures (PJFr) can be a catastrophic complication associated with adult spinal deformity surgery. Presence of osteoporosis has been shown to be one of the risk factors for PJFr. Dural-Energy X-Ray Absorptiometry (DEXA) scans are standard screening tools for diagnosis of osteoporosis. However, spinal DEXA scores have been reported to be flawed with regional sclerosis associated with spinal degeneration representing a possible confounder to the study. Recently, investigators have reported on the use of a computed tomography (CT) scan surrogate in place of spinal DEXA scores.
Source: The Spine Journal - Category: Orthopaedics Authors: Tags: ePosters: Diagnostics/Imaging Source Type: research

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ConclusionsThe newly developed 3D MOI enables distinguishing women with osteoporosis from those with normal BMD with good sensitivity and specificity.Clinical relevanceWhenever a CBCT scan is performed for specific clinical indications, a 3D MOI may be performed to qualitatively and quantitatively assess the condition of the mandibular cortex. This may be surely helpful to assess the osteoporosis status in the ageing population and more specifically in peri- or postmenopausal women.
Source: Clinical Oral Investigations - Category: Dentistry Source Type: research
ConclusionsOur results suggest that hyperostosis of the posterior longitudinal ligament in OPLL may not be associated with bone strength and bone mineral status at the extremities.
Source: Osteoporosis International - Category: Orthopaedics Source Type: research
CONCLUSION: The HUs derived from routine contrast-enhanced abdominal CT scans can be used for the evaluation of osteoporosis, without an additional radiation exposure and cost. PMID: 31731334 [PubMed - as supplied by publisher]
Source: Turkish Journal of Medical Sciences - Category: General Medicine Tags: Turk J Med Sci Source Type: research
AbstractOsteoporosis is a metabolic bone disease with a high prevalence that affects the population worldwide, particularly the elderly. It is often due to fractures associated with bone fragility that the diagnosis of osteoporosis becomes clinically evident. However, early diagnosis would be necessary to initiate therapy and to prevent occurrence of further fractures, thus reducing morbidity and mortality. X-ray-based imaging plays a key role for fracture risk assessment and monitoring of osteoporosis. Whereas over decades dual-energy X-ray absorptiometry (DXA) has been the main method used and still reflects the referenc...
Source: Osteoporosis International - Category: Orthopaedics Source Type: research
AbstractSummaryAssociations of current and previous physical activity (PA) with bone health are unclear. In postmenopausal women with low bone mineral density (BMD), current PA was positively associated with femoral neck BMD and microarchitecture. Past PA was positively associated with tibial microarchitecture. PA appears beneficial for bone health throughout the lifespan.IntroductionTo compare associations of current and past self-reported bone-specific physical activity, and current accelerometer-determined physical activity (PA), with bone structure (bone mineral density [BMD] and microarchitecture) in postmenopausal wo...
Source: Osteoporosis International - Category: Orthopaedics Source Type: research
ConclusionspQCT-FE modeling can provide enhanced diagnostic performance compared with DXA and, given its moderate cost, may be useful in clinical settings.
Source: Osteoporosis International - Category: Orthopaedics Source Type: research
Conclusions: This study suggested that lower BMD and increased loss rate of BMD were associated with a higher risk of carotid calcification plaques in Chinese postmenopausal women. PMID: 31612731 [PubMed - as supplied by publisher]
Source: Climacteric - Category: Geriatrics Authors: Tags: Climacteric Source Type: research
Abstract We investigated the effects of ibandronate, a bisphosphonate; eldecalcitol, an active vitamin D3 analogue; and combination treatment with both agents on secondary osteoporosis and arthritis using rats with adjuvant-induced arthritis. Arthritis was induced in 8-week-old male Lewis rats. Rats were randomized into four treatment groups and an untreated normal control group: ibandronate, eldecalcitol, ibandronate + eldecalcitol, vehicle, and control. Paw thickness was measured to evaluate arthritis. Joint destruction was evaluated histomorphometrically by the ankle joint stained with Fast Green and safranin O...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Source Type: research
Teriparatide has been used to improve bone quality when considering spinal fusion surgery in patients with osteoporosis. Hounsfield units (HU), a standardized measurement for radiodensity, can be obtained on routine computed tomography (CT) scans, while dual energy X-ray absorptiometry (DEXA) is the common test for bone density.
Source: The Spine Journal - Category: Orthopaedics Authors: Source Type: research
AbstractObjectivesTo develop and evaluate a method for areal bone mineral density (aBMD) measurement based on dual-layer spectral CT scout scans.MethodsA post-processing algorithm using a pair of 2D virtual mono-energetic scout images (VMSIs) was established in order to semi-automatically compute the aBMD at the spine similarly to DXA, using manual soft tissue segmentation, semi-automatic segmentation for the vertebrae, and automatic segmentation for the background. The method was assessed based on repetitive measurements of the standardized European Spine Phantom (ESP) using the standard scout scan tube current (30  ...
Source: European Radiology - Category: Radiology Source Type: research
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