Natural medicines for the treatment of fatigue: Bioactive components, pharmacology, and mechanisms

Publication date: Available online 22 August 2019Source: Pharmacological ResearchAuthor(s): Chuanhong Luo, Xiaorong Xu, Xichuan Wei, Wuwen Feng, Haozhou Huang, Haiyan Liu, Runchun Xu, Junzhi Lin, Li Han, Dingkun ZhangAbstractIt is a common phenomenon that people are in a sub-health condition and facing “unexplained fatigue”, which seriously affects their health, work efficiency and quality of life. Meanwhile, fatigue is also a common symptom of many serious diseases such as HIV/AIDS, cancer, and schizophrenia. However, there are still no official recommendations for the treatment of various forms of fatigue. Some traditional natural medicines are often used as health care products, such as ginseng, Cordyceps militaris (L.ex Fr.Link) and Rhodiola rosea L., and these have been reported to have specific anti-fatigue effects with small toxic and side effects and rich pharmacological activities. It may be promising treatment strategy for sub-health. In this review, we first outline the generation of fatigue. Furthermore, we put emphasis on the anti-fatigue mechanism, bioactive components, and clinic trials of natural medicines, which will contribute to the development of potential anti-fatigue agents and open up novel treatments for sub-health.Graphical abstractNatural medicines for the treatment of fatigue: Bioactive components, pharmacology, and mechanisms
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research