Effectiveness of chiropractic manipulation versus sham manipulation on recurrent headaches in children aged 7 –14 years, Protocol for a randomized clinical trial
DiscussionA major strength of this study is its pragmatic nature, where the active treatment group receives chiropractic manipulation according to their individual needs, while both groups continue their use of medication for headache according to their pre-trial habits. Other strengths include an elaborate sham procedure and the weekly outcome reports, reducing recall bias.If it is possible to develop effective treatment for headache in children, a life course of recurring problems may be altered with potential positive implications for both individuals and society.Trial registrationClinicalTrials.gov, identifierNCT02684916.
Conditions: Headache Disorders, Secondary; Post-Dural Puncture Headache; Migraine Disorders; Back Pain; Anesthesia Intervention: Sponsor: Stanford University Active, not recruiting
ConclusionConsistent with research in middle and older adults, physical health conditions are associated with increased risk for the onset of suicidal thoughts and behaviors in adolescents. Mental health screening for adolescents with chronic medical conditions may help parents and physicians identify suicidality early.
Acupuncture might help to reduce opioid use49 for pain management because it has been shown to have clinical effects on several prevalent chronic pain conditions75,76 including osteoarthritis of the knee,78 chronic back pain,10 tension-type headache52 and migraine,45 with effect sizes comparable to other common pharmacological opioid alternatives.7 In addition, acupuncture has shown to be relatively safe,48,79 and it is used by patients.17 It has also been shown to be cost-effective within accepted thresholds.
A study has found that women with menopause symptoms are nearly twice as likely to have chronic pain diagnoses, such as fibromyalgia, migraine, and back pain.
We report a 51-year-old gentleman with composite pheochromocytoma, which is rarer than pheochromocytoma, presenting as severe back pain and lactic acidosis.
Publication date: Available online 7 September 2019Source: Brain, Behavior, and ImmunityAuthor(s): Marie Fitzgibbon, Daniel M Kerr, Rebecca J Henry, David P Finn, Michelle RocheAbstractDepression is a well-recognised effect of long-term treatment with interferon-alpha (IFN-α), a widely used treatment for chronic viral hepatitis and malignancy. In addition to the emotional disturbances, high incidences of painful symptoms such as headache and joint pain have also been reported following IFN-α treatment. The endocannabinoid system plays an important role in emotional and nociceptive processing, however it is unkn...
Endocannabinoid modulation of inflammatory hyperalgesia in the IFN-α mouse model of depression. Brain Behav Immun. 2019 Sep 07;: Authors: Fitzgibbon M, Kerr DM, Henry RJ, Finn DP, Roche M Abstract Depression is a well-recognised effect of long-term treatment with interferon-alpha (IFN-α), a widely used treatment for chronic viral hepatitis and malignancy. In addition to the emotional disturbances, high incidences of painful symptoms such as headache and joint pain have also been reported following IFN-α treatment. The endocannabinoid system plays an important role in emotional and no...
AbstractPurpose of ReviewThis review discusses the recent advancements in research on Cannabinoids ’ role in pain, including its use in cancer pain, neuropathic pain, fibromyalgia, headache, visceral pain, postoperative and failed back pain management, and concurrent use with opioids.Recent FindingsCurrent research suggests that a potential role exists for medical cannabis in pain management, although research shows varied effectiveness by the type of pain. Moreover, its coadministration with opioids may result in reduced opioid requirements.SummaryPatients with neuropathic pain, cancer pain, and migraine headache ma...
A healthy 44-year-old woman developed malaise and severe headache shortly after returning from vacation in Hawaii. As initial symptoms cleared after 24 hours, over the subsequent days, she developed paresthesias in her lower extremities (knees to feet), new-onset urinary retention, and midthoracic radicular pain. Brain MRI revealed nonenhancing lesions in the medulla and midbrain, in addition to punctate subcortical frontal lesions (figure). MRI of the cervical spine revealed 2 nonenhancing lesions at C3-C4 and C6-C7 (figure). She was diagnosed with MS and contemplated disease-modifying therapy (DMT).
CONCLUSIONS: Well-powered studies to truly detect pillow impact on waking symptoms and sleep quality require 400+ symptomatic subjects. CLINICAL REHABILITATION IMPACT: It has previously been reported that using a latex or polyester pillow significantly improves waking cervical symptoms in the general population. This pilot study did not replicate these results in people with known cervical spine degeneration. PMID: 31489809 [PubMed - as supplied by publisher]