Cardioprotective effects of idebenone do not involve ROS scavenging: Evidence for mitochondrial complex I bypass in ischemia/reperfusion injury

In this study, we determined the cardiac and mitochondrial effects of idebenone, a benzoquinone currently in several clinical trials with purported ‘antioxidant’ effects.

Source: Journal of Molecular and Cellular Cardiology - August 21, 2019 Category: Cytology Authors: Justin B. Perry, Grace N. Davis, Mitchell E. Allen, Marina Makrecka-Kuka, Maija Dambrova, Robert W. Grange, Saame Raza Shaikh, David A. Brown Source Type: research