Miscellaneous Perianal Afflictions
This article provides an overview of hidradenitis suppurativa, lichen planus, lichen sclerosis, calcinosis cuti, pyogenic granuloma, intertrigo, and seborrheic keratosis. This article also focuses on recognition and management of these pleomorphic afflictions of the perianal region. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents | Abstract | Full text
Ankita Agrawal, Yugal Kishor SharmaIndian Journal of Dermatology, Venereology, and Leprology 2019 85(6):617-617
Case Summary: A 66-year-old obese (BMI 34) diabetic man, a former smoker who had quit 4 months ago, had a 20-year history of perianal, inguinal, and gluteal hidradenitis suppurativa. He presented to the office with persistent perianal and gluteal inflammation and drainage. He had had various surgical excisions of the affected area over the preceding 10 years. The patient was also following up with dermatology and was previously on doxycycline and infliximab with little improvement in his symptoms. On physical examination of his gluteal and perianal region, he had multiple areas of scarring and draining sinus tracts with ...
Background: Squamous cell carcinoma (SCC), however rare in the anogenital skin, is often locally aggressive. Development of anogenital SCC is related to several other dermatologic and related conditions, including condyloma, lichen planus, hidradenitis suppurativa, Crohn ’s disease, lichen sclerosis and immunosuppression of various etiologies. Even when lesions are detected early, surgical excision can be difficult due to the close proximity of other vital structures, and challenges with primary closure due to the paucity of excess tissue.
We report a case of pityriasis lichenoides chronica (PLC) induced by adalimumab in a patient being treated for hidradenitis suppurativa (HS).
We describe an exceptional case of lichen planus (LP) characterized by marked lymphocytic syringotropism with focal hyperplasia of the eccrine epithelium. Histopathology was characterized by the combination of features of conventional LP, prominent permeation of the secretory portion of the eccrine glands by reactive lymphocytes, and focal involvement of a hair follicle. Syringotropic LP may be regarded as a histologic mimicker of syringotropic MF, thus representing a potential diagnostic pitfall.
This article is protected by copyright. All rights reserved. PMID: 30515753 [PubMed - as supplied by publisher]
The metabolic syndrome —otherwise called syndrome X, insulin resistance syndrome, Reaven syndrome, and “the deadly quartet”—is the name given to the aggregate of clinical conditions comprising central and abdominal obesity, systemic hypertension, insulin resistance (or type 2 diabetes mellitus), and atherogenic dy slipidemia. It is a prothrombotic and proinflammatory state characterized by increased inflammatory cytokine activity. In addition to inflammatory dermatoses such as psoriasis, lichen planus, and hidradenitis suppurativa, metabolic syndrome is also commonly associated with accelerated athe...
Authors: Sand FL, Thomsen SF Abstract Chronic, inflammatory and ulcerating mucocutaneous diseases that can affect the vulvar area are reviewed: lichen sclerosus, lichen planus, plasma cell vulvitis, complex aphthosis, Behcet's disease, pyoderma gangrenosum, metastatic Crohn's disease, dyskeratotic skin diseases (Hailey-Hailey disease and Darier's disease), autoimmune bullous diseases (mucous membrane pemphigoid and pemphigus vulgaris) and hidradenitis suppurativa. Also, vulvodynia and vestibulodynia, zinc and vitamin B deficiency are described. PMID: 28764581 [PubMed - as supplied by publisher]
A number of chronic dermatologic conditions may necessitate long-term adjunctive pain management in addition to treatment of the primary skin disease, such as hidradenitis suppurativa, lichen planus, and other systemic diseases associated with significant pain. Adequate management of chronic pain can represent a unique challenge, but remains an integral component of clinical treatment in relevant contexts. For nociceptive pain of moderate to severe intensity, opioid analgesics can be beneficial when other pain management strategies have failed to produce adequate relief.
ABSTRACT BackgroundVulvar dermatoses are often difficult to classify due to histopathologic overlap. We aimed to report our experience at a single institution. MethodsOne hundred and eighty‐three non‐neoplastic, non‐infectious vulvar biopsies were reviewed. Associations between histopathologic features and specific diagnoses were analyzed by Chi‐squared tests. ResultsTwenty‐two biopsies (12.0%) showed two concurrent processes. A limited differential rather than a definitive diagnosis was rendered in 15 cases (8.2%). The final diagnoses included lichen sclerosus (LS) (38.8%), lichen simplex chronicus (LSC) (29.0%)...