Clinical and dosimetric predictors of physician and patient reported xerostomia following intensity modulated radiotherapy for nasopharyngeal cancer – A prospective cohort analysis

In the last two decades, advances in combining systemic therapy and radiation technology such as intensity modulated radiotherapy (IMRT) have allowed for improved survival with decreased rates of toxicities in nasopharyngeal cancer (NPC) [1 –7]. Several randomized controlled trials have demonstrated the superiority of IMRT in parotid salivary gland sparing and in reducing xerostomia compared to conventional techniques such as two dimensional radiotherapy and 3DCRT (three dimensional conformal radiotherapy) [8–12].

Source: Radiotherapy and Oncology - June 28, 2019 Category: Radiology Authors: Kiattisa Sommat, Ashik Hussain, Whee Sze Ong, Nelson Ling Fung Yit, James Boon Kheng Khoo, Yoke Lim Soong, Joseph Tien Seng Wee, Kam Weng Fong, Terence Wee Kiat Tan Tags: Original Article Source Type: research