Direct access CT for suspicion of brain tumour: an analysis of referral pathways in a population-based patient group

Brain tumour patients see their primary care doctor on average three or more times before diagnosis, so there may be an opportunity to identify ‘at risk’ patients earlier. Suspecting a brain tumour diagnosis i...
Source: BMC Family Practice - Category: Primary Care Authors: Tags: Research article Source Type: research

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Publication date: Available online 24 September 2019Source: NeuroImageAuthor(s): Luciano Simone, Luca Fornia, Luca Viganò, Fabio Sambataro, Marco Rossi, Antonella Leonetti, Guglielmo Puglisi, Henrietta Howells, Andrea Bellacicca, Lorenzo Bello, Gabriella CerriThe development of awake intraoperative brain-mapping procedures for resection of brain tumors is of growing interest in neuroscience, because it enables direct testing of brain tissue, previously only possible in non-human primates. In a recent study performed in this setting specific effects can be induced by direct electrical stimulation on different sectors...
Source: NeuroImage - Category: Neuroscience Source Type: research
CONCLUSION: We reviewed in detail various medical imaging techniques. This paper covers recent developments in detail and elaborates a possible research aspect for the readers in the field. PMID: 31603057 [PubMed - in process]
Source: Current Pharmaceutical Design - Category: Drugs & Pharmacology Authors: Tags: Curr Pharm Des Source Type: research
Publication date: Available online 12 October 2019Source: Life SciencesAuthor(s): Xiao Yu, Maode Wang, Jie Zuo, Alafate Wahafu, Ping Mao, Ruichun Li, Wei Wu, Wanfu Xie, Jia WangAbstractAimsTo investigate the underlying mechanism by which glioblastoma (GBM) cells gain temozolomide (TMZ) resistance and to clarify novel therapeutic targets and new prognostic biomarkers for GBM.Main methodsA genome-wide hierarchical bi-clustering based on previously published microarray databases identified Nuclear Factor I A (NFIA) as one of the most significantly upregulated genes correlated to TMZ resistance in GBM. Then, the potential biol...
Source: Life Sciences - Category: Biology Source Type: research
This study was carried out to elucidate the antineoplastic effect of quercetin through regulating both Notch and Hh pathways, apoptosis, cell proliferation and CK2α activity.Main methodsHepatocellular carcinoma was induced in male Sprague Dawley rats by thioacetamide. Quercetin was administered in both protective and curative doses. Parameters of liver function and oxidative stress were assessed. CK2α, Notch and Hh pathways were evaluated using RT-PCR and ELISA. Apoptosis was investigated by detecting caspase-3, caspase-8 and p53. Proliferative and cell cycle markers as cyclin D1 and Ki-67 were detected immunoh...
Source: Life Sciences - Category: Biology Source Type: research
Conclusion11C-Methionine integrated PET/MRI based texture analysis and conventional features may be a promising noninvasive predictor for differentiating the varied gliomas.
Source: Academic Radiology - Category: Radiology Source Type: research
This study sheds light on a long-standing debate regarding lineage relationships among GSCs and presents a paradigm by which personalized combination therapies can be derived from single-cell RNA signatures, to overcome intra-tumor heterogeneity.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Genome binding/occupancy profiling by high throughput sequencing Other Homo sapiens Source Type: research
Contributors : Chen-Xue Mao ; Zhao-Qian LiuSeries Type : Non-coding RNA profiling by arrayOrganism : Homo sapiensAstrocytoma is a common pathologic type of glioma, its survival and prognosis remain poor.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Non-coding RNA profiling by array Homo sapiens Source Type: research
In conclusion, we performed the largest study so far focused on CSF miRNA profiling in patients with brain tumors, and we believe that this new class of biomarkers have a strong potential as a diagnostic and prognostic tool in these patients.
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research
Our weekly round-up of the best psychology coverage from elsewhere on the web There’s not much evidence that brain training apps really improve our cognitive abilities –  so why do so many people use them? Sabrina Weiss at Wired has the answers. More colour-related research this week: people who live in grey, rainy countries far away from the equator are more likely to associate yellow with joy, reports Eva Frederick in Science. Most people in Finland, for instance, felt that yellow was related to the feeling of joy, while very few of those in countries like Egypt and Saudi Arabia made that associat...
Source: BPS RESEARCH DIGEST - Category: Psychiatry & Psychology Authors: Tags: Weekly links Source Type: blogs
Researchers have recently published 'the first demonstration' that a promising blood test for detecting brain cancer works in the clinic.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Head and Neck Cancer Source Type: news
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