Disc inflammation and Modic changes show an interaction effect on recovery after surgery for lumbar disc herniation

ConclusionsAn interaction effect of MC and disc inflammation by macrophages is present. Only in patients with MC, those with considerable inflammation recover less satisfactory during follow-up after surgery.Graphic abstractThese slides can be retrieved under Electronic Supplementary Material.
Source: European Spine Journal - Category: Orthopaedics Source Type: research

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This study aimed to evaluate the effectiveness of a PLISSIT model sexual counseling to promote sexual function of women with spinal cord injury. In this randomized clinical trial the participants included a total number of 44 women with spinal cord injury randomly assigned to intervention and control groups using random blocking. The intervention group received the PLISSIT sexual counseling in three sessions weekly, and the control group received the routine consultation of the center. Female Sexual Functions of participants were assessed using women ’s Sexual Function Index questionnaires at three times. Two-way rep...
Source: Sexuality and Disability - Category: Disability Source Type: research
Brucella is a facultative anaerobic Gram-negative bacillus. It resembles Mycobacterium tuberculosis and establishes infection intracellularly. Brucella infection shows a strong tissue preference for the reproductive system, bone, and fetal ectoderm (de Figueiredo et al., 2015). Early manifestations of brucellosis consist of fever, sweating, joint pain, symptoms of poisoning, chronic spine arthritis, testis or ovarian inflammation, and neurological complications. The prognosis of brucellosis tends to be poor and can result in disability if an early diagnosis was missed and/or no timely treatment was initiated.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
Semin Musculoskelet Radiol 2019; 23: 376-391 DOI: 10.1055/s-0039-1693661Axial spondyloarthritis (axSpA) is a chronic inflammatory condition that encompasses ankylosing spondylitis as well as nonradiographic axSpA and can lead to chronic pain, structural damage, and disability. The disease is strongly associated with the presence of human leukocyte antigen-B27. Early diagnosis of axSpA is significant due to new treatment regimens leading to reduction of inflammation and potentially delaying disease progression. Imaging of the sacroiliac joints and the spine plays an important role in the early diagnosis of spondyloarthritis...
Source: Seminars in Musculoskeletal Radiology - Category: Radiology Authors: Tags: Review Article Source Type: research
ConclusionsFindings from this study suggest that the FREE approach improves GP concordance with LBP guideline recommendations but does not improve patient recovery outcomes compared with usual care. The FREE approach may reduce unnecessary healthcare use and produce economic benefits. Work participation or health resource use should be considered for primary outcome assessment in future trials of undifferentiated LBP. Trial registrationACTRN12616000888460
Source: PLoS Medicine - Category: Internal Medicine Authors: Source Type: research
Conclusion: A scale for assessing disability in LBP is made available for use in Nigeria and similar populations. Funding: None declared. PMID: 31481808 [PubMed - in process]
Source: Ghana Medical Journal - Category: African Health Tags: Ghana Med J Source Type: research
Abstract Intervertebral disc (IVD) has a pivotal role in the maintenance of flexible motion. IVD degeneration is one of the primary causes of low back pain and disability, which seriously influences patients' health, and increases the family and social economic burden. Recently stem cell therapy has been proven to be more effective on IVD degeneration disease. However, stem cell senescence is the limiting factor in the IVD degeneration treatment. Senescent stem cells have a negative effect on the self-repair on IVD degeneration. In this review, we delineate that the factors such as telomerase shortening, DNA damag...
Source: Current Stem Cell Research and Therapy - Category: Stem Cells Authors: Tags: Curr Stem Cell Res Ther Source Type: research
Abstract OBJECTIVE: Endoscopic discectomy (ED) has been advocated as a less-invasive alternative to open microdiscectomy (OM) and tubular microdiscectomy (TM) for lumbar disc herniations, with the potential to decrease postoperative pain and shorten recovery times. Large-scale, objective comparisons of outcomes between ED, OM, and TM, however, are lacking. The authors' objective in this study was to conduct a meta-analysis comparing outcomes of ED, OM, and TM. METHODS: The PubMed database was searched for articles published as of February 1, 2019, for comparative studies reporting outcomes of some combination...
Source: Journal of Neurosurgery.Spine - Category: Neurosurgery Authors: Tags: J Neurosurg Spine Source Type: research
Complex regional pain syndrome (CRPS) type I and CRPS type II diminish quality of life and can lead to significant disability.15 Both conditions have varied and complex clinical features, with chronic debilitating pain being the primary symptom, usually involving the lower or upper extremities.16,24 The conditions are differentiated by the absence (CRPS-I) or presence (CRPS-II) of demonstrable nerve damage as an underlying etiology.
Source: The Journal of Pain - Category: Materials Science Authors: Source Type: research
CONCLUSIONS: Well-powered studies to truly detect pillow impact on waking symptoms and sleep quality require 400+ symptomatic subjects. CLINICAL REHABILITATION IMPACT: It has previously been reported that using a latex or polyester pillow significantly improves waking cervical symptoms in the general population. This pilot study did not replicate these results in people with known cervical spine degeneration. PMID: 31489809 [PubMed - as supplied by publisher]
Source: European Journal of Physical and Rehabilitation Medicine - Category: Rehabilitation Authors: Tags: Eur J Phys Rehabil Med Source Type: research
Today’s post is another one where there’s very little to guide my thinking… Have you ever wondered why we read so much research looking at the characteristics of the people who look for help with their pain – yet not nearly as much about us, the people who do the helping? There are studies about us – thanks Ben – and others! (Darlow, Dowell, Baxter, Mathieson, Perr &Dean, 2013; Farin, Gramm &Schmidt, 2013; Parsons, Harding, Breen, Foster, Pincus, Vogel &Underwood, 2007). We know some things are helpful for people with pain: things like listening capabilities (Matthias, Ba...
Source: HealthSkills Weblog - Category: Anesthesiology Authors: Tags: Chronic pain Coping strategies Pain conditions Professional topics Research Science in practice attitudes beliefs communication nocebo Source Type: blogs
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