Combination of lithium and electroconvulsive therapy (ECT) is associated with higher odds of delirium and cognitive problems in a large national sample across the United States

In this study, we examine 1) The association and odds of delirium and cognitive problems with ECT and lithium (ECT+Li) combination compared to ECT alone, 2) If positively associated, would this association vary by both type of mood episode and type of disorder?MethodsA national sample of 64,728 adult psychiatric inpatients across the US (identified from a total data of about 70 million total discharges annually) was analyzed using linear-by-linear association and logistic regression to assess the odds ratio (OR) for delirium and cognitive impairment for those treated with lithium (N=158), ECT (N=64148), or ECT+ Li (N=422) after adjusting for demographics and psychiatric diagnoses.ResultsThe prevalence of delirium was higher in the ECT+Lithium group (5.7%) vs. ECT only (0.6%) or lithium only groups (0%). Patients managed with ECT+Lithium have 11.7-fold higher odds (95%CI 7.55–17.99, P
Source: Brain Stimulation - Category: Neurology Source Type: research

Related Links:

Most of us have very specific, vivid ideas about what staying in a psychiatric hospital looks like. These ideas have likely been shaped by Hollywood or sensationalist news stories. Because how often do we hear about someone’s real-life stay at a psychiatric facility? If going to therapy is rarely talked about, the conversations surrounding psychiatric hospitals are virtually non-existent. So we tend to imagine wild, worst-case scenarios. To provide a more accurate picture, we asked several individuals who’ve been hospitalized to share what it was like for them. Of course, every person’s experience is diff...
Source: Psych Central - Category: Psychiatry Authors: Tags: Disorders General Stress Suicide Treatment Bipolar Disorder hope Hospitalization Inspiration Manic Episodes Psychiatric Hospital suicidal Source Type: news
 Schizophrenia does not just affect the person with schizophrenia, but their families, also. This episode of Inside Schizophrenia explores the family relationships impacted by schizophrenia, both immediate and extended.  Two guests join us. The first is Chrisa Hickey, who is the mother of an adult son with schizophrenia and started an online site for parents of children who have a severe mental illness. The other guest, interviewed by co-host Gabe Howard, is Janel Star Withers, mother of host Rachel Star Withers. Janel shares her experiences with raising a schizophrenic daughter.  Host Rachel Star Withers, a d...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Children and Teens Family Inside Schizophrenia Parenting Bipolar disorder and schizophrenia Family Mental Health family mental illness Helping Families in Mental Health Crisis life with schizophrenia Mental Disorder Mental illness and Source Type: blogs
  Schizophrenia does not just affect the person with schizophrenia, but their families, also. This episode of Inside Schizophrenia explores the family relationships impacted by schizophrenia, both immediate and extended.  Two guests join us. The first is Chrisa Hickey, who is the mother of an adult son with schizophrenia and started an online site for parents of children who have a severe mental illness. The other guest, interviewed by co-host Gabe Howard, is Janel Star Withers, mother of host Rachel Star Withers. Janel shares her experiences with raising a schizophrenic daughter.  Host Rachel Star Withers, ...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Children and Teens Family General Inside Schizophrenia Mental Health and Wellness Parenting Bipolar disorder and schizophrenia Family Mental Health family mental illness Helping Families in Mental Health Crisis life with schizophrenia Source Type: blogs
Pharmacopsychiatry DOI: 10.1055/a-0991-0582The treatment of depressive episodes remains complicated by the long latency of antidepressant efficacy, insufficient response, and high risk of suicide. Ketamine and esketamine have been proposed as fast-acting substances able to overcome these impediments.Since the first randomized controlled trial in the year 2000, numerous studies have explored the antidepressant efficacy of ketamine and esketamine. Clear evidence has emerged that a single infusion exerts a significant antidepressant and antisuicidal effect in both unipolar and bipolar depression. A few studies suggest that an...
Source: Pharmacopsychiatry - Category: Psychiatry Authors: Tags: Review Source Type: research
Conditions:   Depressive Disorder, Major;   Depression, Bipolar Intervention:   Device: Electroconvulsive therapy Sponsor:   Region Örebro County Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Belz M, Methfessel I, Spang M, Besse M, Folsche T, Stephani C, Zilles D Abstract Clinical response to electroconvulsive therapy (ECT) depends on eliciting a generalized seizure. Though there are multiple ictal and other parameters to assess seizure quality, factors that influence these parameters have only been identified to a limited extend in antecedent studies (e.g., stimulus dosage, age). In the context of ECT, electrolyte concentrations have hardly been investigated so far-although hyponatremia is one well-known clinical factor to increase the risk of spontaneous seizures. In 31 patients with unipolar...
Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research
More News: Bipolar | Brain | Depression | Electroconvulsive Therapy | Lithium | Mania | Neurology | Psychiatry | Study | USA Health