Using High Sensitivity Troponin to Rule Out Myocardial Infarction

Publication date: September 2019Source: Annals of Emergency Medicine, Volume 74, Issue 3Author(s): Dan Mayer
Source: Annals of Emergency Medicine - Category: Emergency Medicine Source Type: research

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Publication date: Available online 17 September 2019Source: The Annals of Thoracic SurgeryAuthor(s): Sung Jun Park, Ho Jin Kim, Joon Bum Kim, Sung-Ho Jung, Suk Jung Choo, Jae Won Lee, Cheol Hyun ChungABSTRACTBackgroundAlthough multi-arterial grafting or bilateral mammary artery use is being increasingly emphasized more than ever for this contemporary CABG practice, saphenous vein graft (SVG) is still the most frequently used CABG conduit, accounting for 80% of all CABG conduits. Researches focusing on modifiable surgical factors such as anastomosis technique, however, has been scarcely conducted; this study aims to compare...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Authors: Iyer KS, Dayal S Abstract Platelets are small, anucleated effector cells that play an important role in linking the hemostatic and inflammatory processes in the body. Platelet function is known to be altered under various inflammatory conditions including aging. A gain in platelet function during aging can increase the risk of thrombotic events, such as stroke and acute myocardial infarction. Anti-platelet therapy is designed to reduce risk of serious cerebrovascular and cardiovascular events, but the adverse consequences of therapy, such as risk for bleeding increases with aging as well. Age-associated co...
Source: Platelets - Category: Hematology Tags: Platelets Source Type: research
Publication date: October 2019Source: American Journal of Preventive Medicine, Volume 57, Issue 4Author(s): Talal Alzahrani, Stanton A. Glantz
Source: American Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Publication date: October 2019Source: American Journal of Preventive Medicine, Volume 57, Issue 4Author(s): Michelle T. Bover Manderski, Binu Singh, Cristine D. Delnevo
Source: American Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
FTY720 is a sphingosine 1 phosphate (S1P) receptor agonist approved for the treatment of multiple sclerosis, which is a chronic inflammatory autoimmune disorder. Sepsis is a complex syndrome associated with progressive endotoxemic developments, which finally leads to damage of multiple organs, including the heart. In critical patients, cardiovascular dysfunction due to sepsis is a major cause of death. Previous studies have shown an association between S1P and cardioprotection in the situation of ischemia reperfusion and myocardial infarction. Therefore, we will study the role of S1P towards endotoxic cardiomyocytes. Diffe...
Source: Shock - Category: Emergency Medicine Tags: Basic Science Aspects Source Type: research
Ventrix, a spin-off company of the University of California San Diego, has developed a special hydrogel that can be injected into the heart to provide a platform for cardiac repair following a heart attack. The technology was just tested in humans fo...
Source: Medgadget - Category: Medical Devices Authors: Tags: Cardiac Surgery Cardiology Materials Source Type: blogs
We examined the plasma S100A1 level in 207 STEMI patients (STEMI group) and 217 clinically healthy subjects for routine physical examination without a history of coronary artery disease (Control group). Baseline characteristics and concentrations of relevant biomarkers were compared. The relationship between S100A1 and other plasma biomarkers was detected using correlation analysis. The predictive role of S100A1 on occurrence of STEMI was then assessed using multivariate ordinal regression model analysis after adjusting for other covariates. RESULTS: The plasma S100A1 level was found to be significantly higher (P
Source: International Journal of Medical Sciences - Category: Biomedical Science Tags: Int J Med Sci Source Type: research
Recently, several randomized trials have noted improved outcomes with staged percutaneous coronary intervention (PCI) of nonculprit vessels in patients with ST-segment elevation myocardial infarction (STEMI) a...
Source: Cardiovascular Diabetology - Category: Cardiology Authors: Tags: Original investigation Source Type: research
Psoriasis, a chronic inflammatory skin disease is associated with heightened immune activation, accelerated cardiovascular (CV) risk as well as increased acute coronary syndromes, most evident in young adults (Gelfand et al., 2006). This inflammatory skin disease confers an independent risk for myocardial infarction (MI) beyond traditional CV risk factors (Mehta et al., 2010) and on average leads to a decreased lifespan of five years (Gelfand et al., 2006). One explanation is the susceptibility of psoriasis patients to develop unstable, lipid-rich non-calcified coronary plaques (NCB) that are vulnerable to rupture (Lerman et al., 2017).
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Letters to the Editor Source Type: research
Von Willebrand factor (VWF) plays an important role in thrombogenesis and mediates platelet adhesion particularly under high shear stress. Such conditions are generally found in stenotic arteries and can eventually cause myocardial infarction or stroke.
Source: Atherosclerosis - Category: Cardiology Authors: Source Type: research
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