Therapeutic potential of ethyl acetate fraction of Tephrosia purpurea Linn. leaves in a rat model of gout

ConclusionEATP lowered the serum uric acid level and increased the urine uric acid level through excretion, which is useful in the treatment of gout. Hence the EATP was found to be helpful in the treatment of gout.
Source: Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research

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Conditions:   Uncontrolled Gout;   Kidney Transplant Intervention:   Biological: Pegloticase Sponsor:   Horizon Pharma Rheumatology LLC Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Uncontrolled Gout;   Kidney Transplant Intervention:   Biological: Pegloticase Sponsor:   Horizon Pharma Rheumatology LLC Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Uncontrolled Gout;   Kidney Transplant Intervention:   Biological: Pegloticase Sponsor:   Horizon Pharma Rheumatology LLC Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Abstract Calcification in hyaline and fibrocartilage is caused by the deposition of calcium pyrophosphate dehydrate, commonly referred to as chondrocalcinosis. Clinically, this can lead to arthritis symptoms similar to a gout attack -"pseudogout". Nonetheless, also chronic or asymptomatic disease courses are possible. The prevalence of chondrocalcinosis increases with age. The diagnostic workup of degenerative joint disease, therefore, often reveals calcifications of articular cartilage as harmless incidental findings. However, particularly in patients younger than 60 years of age, chondrocalci...
Source: Der Orthopade - Category: Orthopaedics Authors: Tags: Orthopade Source Type: research
In this study, SUA, CRP, creatinine, MCP-1, IFN- α2, IFN-γ, Il-1β, IL-6, IL-8, IL-10, IL-12, IL-17a, IL-18, IL-23, IL-33, TNF-α, and allantoin levels were measured prior to and after 3 months of TNFis treatment in patients with SARDs. The values obtained in the biochemical assays were then tested for associations with the patients’ demograp hic and disease-related data. A total of 128 patients (rheumatoid arthritis,n = 44; ankylosing spondylitis,n = 45; psoriatic arthritis,n = 23; and adults with juvenile idiopathic arthritis,n = 16) ...
Source: Rheumatology International - Category: Rheumatology Source Type: research
Our body is flexible due the joints. These joints connect two bones, provide support and help in the body parts movement. Joint pain is a feeling of discomfort, aches and soreness in any of our body ’s joint. There have been lots of cases of people having aches in their joints. These joint pains are due to injuries affecting the ligaments, bursae, or tendons surrounding the joint. Pain in the joints is also due to infection and inflammation and in an extremely rare case because of cancer. It becomes extremely painful when you try to move your body parts suffering this pain.There are different conditions which are res...
Source: radRounds - Category: Radiology Authors: Source Type: blogs
CONCLUSIONS: Seasonal variations in infectious agents, sun exposure, and food ingestion during gestation or early infancy seem to explain the association between birth month/season and development of rheumatic diseases. PMID: 31498065 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
This article outlines 10 tips on the use of DECT imaging of the musculoskeletal system, explaining the technique and indications with practical suggestions to help guide the radiologist. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Seminars in Musculoskeletal Radiology - Category: Radiology Authors: Tags: Review Article Source Type: research
MONDAY, Sept. 9, 2019 -- Gout is associated with an elevated risk for chronic kidney disease (CKD) progression, according to a study published online Aug. 28 in BMJ Open. Austin G. Stack, M.B.B.Ch., M.D., from the University of Limerick in Ireland,...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Studies on comorbidities seen with CKD reviewed here examine controlled vs uncontrolled gout, psychiatric diagnoses, and screening for intracranial aneurysm.
Source: ConsultantLive - Category: Internal Medicine Tags: Kidney Disease Source Type: news
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