Optimum lesion set and predictors of outcome in persistent atrial fibrillation ablation: a meta-regression analysis

Conclusion  Linear ablation, PWI, and CFAE ablation improves intraprocedural AF termination, but such termination does not predict better long-term outcomes. Study arms including PWI or LAA isolation in the lesion set were associated with improved outcomes in terms of freedom from AF; however, further randomized trials are required before these can be routinely recommended. Left atrial size is the most important marker of AF chronicity influencing outcomes.
Source: Europace - Category: Cardiology Source Type: research

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This study proposed an approach based on deep learning that combined convolutional neural networks (CNNs) and long short-term memory networks (LSTM) to automatically identify six types of ECG signals: normal (N) sinus rhythm segments, atrial fibrillation (AFIB), ventricular bigeminy (B), pacing rhythm (P), atrial flutter (AFL), and sinus bradycardia (SBR). The proposed network applied a multi-input structure to process 10 s ECG signal segments and corresponding RR intervals from the MIT-BIH arrhythmia database. With a five-fold cross-validation strategy, this network achieved 99.32 % accuracy. Then, the diversity of the ...
Source: Biomedical Signal Processing and Control - Category: Biomedical Science Source Type: research
DiscussionThe interventions of education and medication alerts resulted in a significant increase in the percentage of patients receiving appropriate doses of dilTIAZem and a nonsignificant decrease in the incidence of hypotension. This process-oriented intervention resulted in an improvement in appropriate dilTIAZem doses at our site. Rate control was not statistically significantly different between the 2 groups. Long-term sustainability of this intervention requires further study.
Source: Journal of Emergency Nursing - Category: Nursing Source Type: research
Publication date: Available online 12 December 2019Source: Canadian Journal of CardiologyAuthor(s): Christopher C. Cheung, Thomas M. Roston, Jason G. Andrade, Matthew T. Bennett, Margot K. DavisAbstractCardiac amyloidosis occurs secondary to the deposition of insoluble protein fibrils in cardiac tissue leading to progressive myocardial dysfunction, clinical heart failure, and arrhythmia. In recent years, increasing awareness and improved screening have resulted in an increased prevalence of cardiac amyloidosis, with contemporary estimates reporting a prevalence of 18 to 55 cases per 100,000 person-years, and accounting for...
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
CONCLUSIONS: Although with a low number of pooled events, there was a trend for a lower post-procedure stroke in TMVR when compared with SMVR and a similar one between TMVR and OMT alone. PMID: 31829941 [PubMed - as supplied by publisher]
Source: EuroIntervention - Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research
ConclusionsPatients with peAF unresponsive to ablation show high surface and intracardiac DFs indicative of severe and uniform bi-atrial remodeling.
Source: Journal of Interventional Cardiac Electrophysiology - Category: Cardiology Source Type: research
We appreciate the thoughtful feedback regarding our manuscript by Drs. Lattanzi and Silvestrini. We agree that serologic and physiologic biomarkers of other occult stroke mechanisms would add to our understanding and management of these patients. In regard to occult cardiac sources of embolism, elevations in the brain natriuretic peptide,1 and larger P-wave terminal force (PWTF)2 or left atrial diameter3 are increasingly thought to be markers of a prothrombotic cardiopathy. As previously shown by Dr.
Source: Journal of Stroke and Cerebrovascular Diseases - Category: Neurology Authors: Tags: Letter to the Editor Source Type: research
AbstractAtrial fibrillation is the most common sustained arrhythmia encountered in primary care practice and represents a significant burden on the health care system with a higher than expected hospitalization rate from the emergency department. The first goal of therapy is to assess the patient ’s symptoms and hemodynamic status. There are multiple acute management strategies for atrial fibrillation including heart rate control, immediate direct-current cardioversion, or pharmacologic cardioversion. Given the variety of approaches to acute atrial fibrillation, it is often difficult to co nsistently provide cost-eff...
Source: Internal and Emergency Medicine - Category: Emergency Medicine Source Type: research
Source: Journal of Thrombosis and Thrombolysis - Category: Hematology Source Type: research
Atrial fibrillation (AF) is a growing epidemic in the aging world population [1]. In many patients AF can be asymptomatic leading to an underestimation of its true prevalence and incidence. Conceptually, AF is increasingly considered the consequence of an atrial cardiomyopathy that results from the combined effects of genetic predisposition, risk factors and co-morbidities [2]. Once AF occurs, it causes changes in the structure and function of the atria (atrial remodelling), which promote AF re-initiation and maintenance [3].
Source: International Journal of Cardiology - Category: Cardiology Authors: Source Type: research
AliveCor is close to our hearts. Literally. David Albert, the co-founder of the company, started experimenting with handheld, wireless ECG devices in the late 90s. Approximately 10 years later we tried out their FDA-cleared, medical grade gadget. It was a truly inspiring moment. Needless to say, we’ve been keeping track of their journey ever since. In our eyes Kardia is the textbook example of technology shaping health care, empowering and supporting not only e-patients, but medical professionals as well. So, let’s take a look at their newest creation, the KardiaMobile6L! Why did the chicken cross the ro...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Health Sensors & Trackers cardiology ecg fda Healthcare heart technology Source Type: blogs
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