Cancers, Vol. 11, Pages 1225: Key Role of Obesity in Genitourinary Tumors with Emphasis on Urothelial and Prostate Cancers

Conclusions: The main focus of this review was to understand the interplay between obesity/BMI and UC/PCa. Several pathogenic cellular pathways exploring the issue are discussed, opening the way to challenging tailored treatments on the basis of BMI. Improving the knowledge of molecular connections between obesity and UC and PCa could favor the development of new therapies likely reducing chemo- and immunotherapy drug resistance.

Source: Cancers - August 21, 2019 Category: Cancer & Oncology Authors: Matteo Santoni Alessia Cimadamore Francesco Massari Francesco Piva Gaetano Aurilio Angelo Martignetti Marina Scarpelli Vincenzo Di Nunno Lidia Gatto Nicola Battelli Liang Cheng Antonio Lopez-Beltran Rodolfo Montironi Tags: Review Source Type: research