A novel RNA variant of human concentrative nucleoside transporter 1 (hCNT1) that is a potential cancer biomarker

ConclusionWe have identified a novel intron retaining and exon skipping splice variant of the hCNT1 nucleoside transporter, and designated it hCNT1-IR, which has a similar tissue expression distribution as the normal hCNT1 variant, but unlike the normal transcript, hCNT1-IR is overexpressed in some cancers and may serve as a potential cancer biomarker.

http://link.springer.com/10.1186/s40164-019-0144-y

Source: Experimental Hematology and Oncology - August 21, 2019 Category: Cancer & Oncology Source Type: research