Generation of two induced pluripotent stem cell lines from patients with unbalanced translocation (3;22)

Publication date: Available online 21 August 2019Source: Stem Cell ResearchAuthor(s): Yanyan Ma, Haiyan Zhang, Xiaomeng Yang, Yue Li, Jingyun Guan, Kaihui Zhang, Yan Huang, Guangjin Pan, Zhongtao Gai, Yi LiuAbstractHere we describe the generation and characterization of the human induced pluripotent stem cell (iPSC) lines from urine-derived cells (UCs) from two patients with unbalanced chromosomal translocation t(3,22)(q28;q13.3). The iPSC lines retain the original chromosome abnormality, express pluripotency markers and bear differentiation potential.
Source: Stem Cell Research - Category: Stem Cells Source Type: research