SNHG16 promotes osteosarcoma progression and enhances cisplatin resistance by sponging miR-16 to upregulate ATG4B expression.

CONCLUSIONS: Overall, our findings showed the importance of the regulatory axis of SNHG16/miR-16/ATG4B underlying osteosarcoma progression and chemoresistance to cisplatin. This research would benefit the therapy development in the treatment of osteosarcoma. PMID: 31427084 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31427084?dopt=Abstract

Source: Biochemical and Biophysical Research communications - August 15, 2019 Category: Biochemistry Authors: Liu Y, Gu S, Li H, Wang J, Wei C, Liu Q Tags: Biochem Biophys Res Commun Source Type: research