Exosomal microRNA-122 mediates obesity-related cardiomyopathy through suppressing mitochondrial ADP-ribosylation factor-like 2

In conclusions, our present study firstly showed that liver-secreted exosomal miR-122 played a critical role in the development of metabolic cardiomyopathy, and miR-122/mitochondrial Arl-2 signaling affected cardiac energy homeostasis.

Source: Clinical Science - August 20, 2019 Category: Biomedical Science Authors: Wang, Y., Jin, P., Liu, J., Xie, X. Tags: PublishAheadOfPrint Source Type: research