Placental structure in gestational diabetes mellitus

This article is part of a Special Issue entitled: Membrane Transporters and Receptors in Pregnancy Metabolic Complications edited by Luis Sobrevia.Graphical abstract
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - Category: Molecular Biology Source Type: research

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Conclusion: The discovery of these biomarkers provided a new theoretical basis and experimental basis for further study of the early diagnosis and pathogenesis of GDM. At the same time, LC-MS-based serum metabolomics methods also showed great application values in disease diagnosis and mechanism research.
Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research
Publication date: November 2019Source: European Journal of Obstetrics &Gynecology and Reproductive Biology, Volume 242Author(s): Michael Lavie, Inbar Lavie, Sharon MaslovitzAbstractBackgroundPaleolithic diet has recently gained popularity due to its presumed health benefits. The favorable metabolic effects of this diet were assessed in non-pregnant population but its impact during pregnancy remains to be evaluated.Study designA retrospective cohort study comparing two groups. Group A comprised of women with singleton low-risk pregnancy adherent to paleolithic diet throughout gestation (n = 37). Group B comprised lo...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
Authors: Shindo R, Aoki S, Kasai J, Saigusa Y, Nakanishi S, Miyagi E Abstract To estimate pregnancy complications in women newly diagnosed with gestational diabetes mellitus (GDM) according to the new International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria and verify the validity of introducing the IADPSG criteria in Japan. This retrospective study included data from women with singleton delivery at 22 weeks or later at a tertiary hospital during 2000-2009. We compared pregnancy outcomes between women who would now be diagnosed with GDM according to the IADPSG criteria but not by the old ...
Source: Endocrine Journal - Category: Endocrinology Tags: Endocr J Source Type: research
Globally, Gestational Diabetes Mellitus (GDM) is rising, but it is a neglected health threat to mothers and their children in low resource countries. Although, GDM is known in Ethiopia, information regarding i...
Source: BMC Pregnancy and Childbirth - Category: OBGYN Authors: Tags: Research article Source Type: research
Pre-gestational and gestational diabetes mellitus are common complications in pregnancy affecting one in six pregnancies. The maternity services are under significant strain managing the increasing number of c...
Source: BMC Health Services Research - Category: General Medicine Authors: Tags: Research article Source Type: research
by Yeyi Zhu, Mengying Li, Mohammad L. Rahman, Stefanie N. Hinkle, Jing Wu, Natalie L. Weir, Yuan Lin, Huixia Yang, Michael Y. Tsai, Assiamira Ferrara, Cuilin Zhang BackgroundDespite dietary recommendations of polyunsaturated fatty acids (PUFAs) for cardiometabolic health, n-3 and n-6 PUFAs and their interplay in relation to diabetes risk remain debated. Importantly, data among pregnant women are scarce. We investigated individual plasma phospholipid n-3 and n-6 PUFAs in early to midpregnancy in relation to subsequent risk of gestational diabetes mellitus (GDM). Methods and findingsWithin the National Institute of Child Hea...
Source: PLoS Medicine - Category: Internal Medicine Authors: Source Type: research
In conclusion, RA treatment could increase the activity of the antioxidant enzyme, suppress the oxidative stress, inflammation response and activation of NF-κB signaling, thereby improving blood glucose level and cardiac injury of GDM mice before and after delivery. PMID: 31518508 [PubMed - as supplied by publisher]
Source: Canadian Journal of Physiology and Pharmacology - Category: Drugs & Pharmacology Authors: Tags: Can J Physiol Pharmacol Source Type: research
Publication date: Available online 11 September 2019Source: Reproductive BioMedicine OnlineAuthor(s): Jingwen Lang, Bingqian Zhang, Yueru Meng, Yanzhi Du, Linlin Cui, Weiping LiABSTRACTResearch QuestionAre maternal depression and anxiety disorders (MDAD) before and during pregnancy associated with in vitro fertilization (IVF) outcomes?DesignA total of 5556 women with their first IVF cycle started between August 15th, 2014, and December 31st, 2015 were pooled from a prospective cohort of assisted reproductive technology (ART) children. The self-rating depression scale (SDS) and self-rating anxiety scale (SAS) were used to d...
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
Authors: Alamolhoda SH, Yazdkhasti M, Namdari M, Zakariayi SJ, Mirabi P Abstract Studies that examined the impacts of inflammatory factors on gestational diabetes mellitus (GDM) are very sparse. The purpose of this study was to investigate the relationship between C-reactive protein (CRP) and the risk of GDM. Pregnant women who fulfilled the inclusion criteria and their gestational ages were below 10 weeks were recruited to this cohort study and were followed up until the 24-28 weeks of gestation. At the first pre-natal care visit blood samples were taken from all the pregnant women to investigate the...
Source: Journal of Obstetrics and Gynaecology - Category: OBGYN Tags: J Obstet Gynaecol Source Type: research
by Tawanda Chivese, Shane A. Norris, Naomi S. Levitt BackgroundGlobal data indicate that women with a history of hyperglycemia first detected in pregnancy (HFDP) are at up to 7 times risk of progressing to type 2 diabetes mellitus (T2DM) compared with their counterparts who have pregnancies that are not complicated by hyperglycemia. However, there are no data from the sub-Saharan African region, which has the highest projected rise in diabetes prevalence globally. The aim of this study was to determine the proportion of women who progress to T2DM and associated risk factors 5 to 6 years after HFDP in Cape Town, South Afric...
Source: PLoS Medicine - Category: Internal Medicine Authors: Source Type: research
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