Diabetes and Chronic Kidney Disease Basics: Part Two

The primary meal planning goal for diabetes includes maintaining consistency in the amount of carbohydrate consumed at meals. Coupled with the restrictions required for renal disease, this meal plan does require ongoing education from a registered dietitian nutritionist with experience with diabetic kidney disease (DKD). Diet changes are dictated by the laboratory values, specifically serum phosphorus and serum potassium. Each organization stipulates slightly different recommendations for these nutrients.
Source: Journal of Renal Nutrition - Category: Urology & Nephrology Authors: Tags: Patient Education Source Type: research

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Publication date: Available online 15 September 2019Source: The LancetAuthor(s): Rajiv Agarwal, Patrick Rossignol, Alain Romero, Dahlia Garza, Martha R Mayo, Suzette Warren, Jia Ma, William B White, Bryan WilliamsSummaryBackgroundSpironolactone is effective at reducing blood pressure in patients with uncontrolled resistant hypertension. However, the use of spironolactone in patients with chronic kidney disease can be restricted by hyperkalaemia. We evaluated use of the potassium binder patiromer to allow more persistent use of spironolactone in patients with chronic kidney disease and resistant hypertension.MethodsIn this ...
Source: The Lancet - Category: General Medicine Source Type: research
Authors: Liebenthal R, Butler S, Coppola J, Shah B Abstract BACKGROUND: Use of a universal diagnostic catheter may decrease procedural time and catheter-exchange related spasm when compared with a dual-catheter strategy. The aim of this study was to identify preprocedural predictors of failure to complete a coronary angiogram with a universal catheter alone. METHODS: Consecutive patients (n = 782) who underwent a right transradial/transulnar coronary angiogram with a single operator were retrospectively reviewed. Multivariable predictors of failure to complete the procedure with a universal catheter alone were ...
Source: The Journal of Invasive Cardiology - Category: Cardiology Tags: J Invasive Cardiol Source Type: research
Publication date: Available online 14 September 2019Source: Journal of Vascular and Interventional RadiologyAuthor(s): Edwin A. Takahashi, William S. Harmsen, Sanjay MisraAbstractPurposeTo determine the impact of renal function trajectory, defined as the change in renal function over time before and after renal artery stent placement, on long-term risk for renal replacement therapy (RRT) and mortality.Materials and MethodsEstimated glomerular filtration rates (eGFRs) 6–12 months before renal artery stent placement, at the time of intervention, and 6–12 months after intervention were determined in 398 patients. ...
Source: Journal of Vascular and Interventional Radiology - Category: Radiology Source Type: research
llo Persico Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide and its incidence is definitely increasing. NAFLD is a metabolic disease with extensive multi-organ involvement, whose extra-hepatic manifestations include type 2 diabetes mellitus, cardiovascular disease, obstructive sleep apnea, chronic kidney disease, osteoporosis, and polycystic ovarian syndrome. Recently, further evidence has given attention to pathological correlations not strictly related to metabolic disease, also incorporating in this broad spectrum of systemic involvement hypothyroidism, psoriasis,...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Review Source Type: research
This study aimed to evaluate the effect of chronic blockade of ET-1 receptor with MAC on the alteration of renal function observed in hypertensive and hyperglycemic animals. Genetically hypertensive rats were divided into control hypertensive (HT-CTL) group, hypertensive and hyperglycemic (HT+DIAB) group, and hypertensive and hyperglycemic group that received 25 mg/kg macitentan (HT-DIAB+MAC25) via gavage for 60 days. Kidney function and parameters associated with oxidative and nitrosative stress were evaluated. Immunohistochemistry for neutrophil gelatinase-associated lipocalin (NGAL), ET-1, and catalase in the renal cort...
Source: Jornal Brasileiro de Nefrologia - Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
ConclusionAlthough the investigated co-morbidities are capable or inducing pathophysiological changes that are predisposing factors for tumor progression, none is an independent prognostic factor in patients with RCC.
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research
Healthy.io has developed an interesting use for smartphones. The Tel Aviv, Israel-based Company is turning the smartphone into a clinical-grade medical device to be used in the aid of diagnosing chronic kidney disease (CKD). Healthy.io’s ACR test has received FDA clearance and in addition, the firm has closed a $60 million Series C funding round led by Corner Ventures with participation by Joy Capital and all previous investors: Ansonia Holdings, Aleph, and Samsung NEXT. The funding round will be used to accelerate Healthy.io’s global expansion and product development. Additionally, the ...
Source: MDDI - Category: Medical Devices Authors: Tags: Digital Health Source Type: news
Conclusions: In elective hip and knee surgery, compared with non-CKD patients, CKD patients showed worse health conditions. Due to a higher rate of comorbidities and complications in CKD patients, they should be treated carefully during perioperative periods. PMID: 31500490 [PubMed - as supplied by publisher]
Source: Journal of Investigative Surgery - Category: Surgery Tags: J Invest Surg Source Type: research
Abstract The incidence of diabetes mellitus has significantly increased among women of childbearing age and it has been shown that prenatal exposure to maternal diabetes increases the risk of associated congenital anomalies of the kidney. Congenital anomalies of the kidney are amongst the leading causes of chronic kidney disease in children. To better understand the effect of maternal diabetes on kidney development, we analyzed wildtype offspring (DM_Exp) of diabetic Ins2+/C96Ymice (Akitamice). DM_Exp mice at postnatal day 34 (P34) have a reduction of approximately 20% in the total nephron number compared to contr...
Source: American Journal of Physiology. Renal Physiology - Category: Physiology Authors: Tags: Am J Physiol Renal Physiol Source Type: research
We examined human lung tissue from COPD patients and normal control subjects, and found a substantial increase in p16-expressing alveolar cells in COPD patients. Using a transgenic mouse deficient for p16, we demonstrated that lungs of mice lacking p16 were structurally and functionally resistant to CS-induced emphysema due to activation of IGF1/Akt regenerative and protective signaling. Fat Tissue Surrounds Skeletal Muscle to Accelerate Atrophy in Aging and Obesity https://www.fightaging.org/archives/2019/09/fat-tissue-surrounds-skeletal-muscle-to-accelerate-atrophy-in-aging-and-obesity/ Researchers her...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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