Practical points for applying herpes zoster vaccine recommendations

This article highlights practical considerations to help clinicians appropriately apply the most recent vaccine recommendations to their patients.
Source: The Nurse Practitioner - Category: Nursing Tags: Feature: IMMUNIZATIONS Source Type: research

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UK Abstract In patients with multiple sclerosis (MS) primary varicella zoster virus (VZV) infections (chickenpox) or reactivation (shingles, herpes zoster) pose a particular challenge for neurologists and physicians in everyday clinical practice. On the one hand the various immunotherapeutic agents for treatment of MS have differently expressed risks for VZV-associated infections and on the other hand the currently available vaccination strategies (dead vs. live vaccines, single vs. combination vaccines) require an individualized approach. Moreover, in addition to the optimal timing of vaccination during the...
Source: Der Nervenarzt - Category: Neurology Authors: Tags: Nervenarzt Source Type: research
Condition:   Herpes Zoster Interventions:   Biological: Herpes Zoster subunit (HZ/su) vaccine (GSK1437173A);   Drug: Placebo Sponsor:   GlaxoSmithKline Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
This Medical News article examines the increasing incidence of herpes zoster ophthalmicus —shingles of the eye—and the need for more widespread vaccination against shingles.
Source: JAMA - Journal of the American Medical Association - Category: General Medicine Source Type: research
Abstract Varicella zoster and herpes zoster are infections caused by the highly contagious varicella-zoster virus (VZV). Despite widespread availability of vaccines against VZV, as well as varicella vaccination rates>95%, VZV remains a public health concern because of several common myths and misconceptions. Because of the success of routine varicella vaccination programs, some people mistakenly believe that varicella and herpes zoster are now no longer a threat to public health. Another common misconception is that shingles is less infectious than varicella; however, clinical evidence indicates otherwise. Seve...
Source: Clinical Therapeutics - Category: Drugs & Pharmacology Authors: Tags: Clin Ther Source Type: research
Abstract Herpes zoster (HZ), also known as shingles, results from reactivation of the latent varicella-zoster virus (VZV), which commonly causes chickenpox in childhood. Greater than 90% of adults are infected with this virus, putting them at risk for reactivation. HZ presents as a painful, vesicular rash distributed in a unilateral and dermatomal pattern along dorsal root or cranial nerve ganglia. The rash often presents with prodromal symptoms and progresses to include clear vesicular clusters, evolving through stages of pustulation, ulceration, and crusting. HZ therapy currently involves the use of antiviral ag...
Source: Skin Therapy Letter - Category: Dermatology Authors: Tags: Skin Therapy Lett Source Type: research
The clear tissue at the front of the eye is known as the cornea, and it must remain crystal clear in order for an individual to see clearly. The herpes viruses can infect the cornea, causing damage to tissue and possibly causing lasting visual impairment if not quickly identified and treated. Herpes simplex: the cold sore virus One of the most common infections of the cornea is caused by the herpes simplex virus (HSV type I and HSV type II), or the cold sore virus. The most common question from patients with HSV infection of the cornea is “How did I get this?” The answer is fairly simple. The virus is everywher...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Eye Health Infectious diseases Source Type: blogs
Christine I. Alston1,2 and Richard D. Dix1,2* 1Department of Biology, Viral Immunology Center, Georgia State University, Atlanta, GA, United States 2Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, United States Suppressor of cytokine signaling (SOCS) proteins provide selective negative feedback to prevent pathogeneses caused by overstimulation of the immune system. Of the eight known SOCS proteins, SOCS1 and SOCS3 are the best studied, and systemic deletion of either gene causes early lethality in mice. Many viruses, including herpesviruses such as herpes simplex virus and cytomega...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Authors: Klaric JS, Beltran TA, McClenathan BM Abstract Herpes zoster (HZ, shingles) affects individuals (60+ years) by reactivation of varicella virus from primary infection. Approximately one-third of the general population will develop HZ and are at increased risk of stroke. Our objective was describing possible associations between self-reported HZ vaccination and stroke with the Centers for Disease Control and Prevention's Behavioral Risk Factors Surveillance System, a cross-sectional nationwide telephone survey. Non-institutionalized U.S. adults answered items concerning health risk behaviors. 2014 survey dat...
Source: Military Medicine - Category: International Medicine & Public Health Tags: Mil Med Source Type: research
AbstractHerpes zoster (shingles) is the reactivation of dormant varicella zoster virus in individuals who previously experienced varicella infection or vaccination. Herpes zoster can occur in pregnancy, although it is rare. This case report describes the clinical presentation and diagnosis of herpes zoster and reviews current recommendations for treatment. Preventative measures and the role of immunization are discussed in addition to clinical implications for intrapartum, postpartum, and newborn care to guide practitioners in caring for women experiencing or exposed to herpes zoster in pregnancy.
Source: Journal of Midwifery and Women's Health - Category: Midwifery Authors: Tags: Clinical Rounds Source Type: research
The higher risk for stroke with herpes zoster was not attenuated by antivirals or Zostavax vaccination in older patients, but that shouldn't slow vaccination rates or further study.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Cardiology News Source Type: news
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