Mupirocin Resistance in Staphylococcus aureus: A Systematic Review and Meta-Analysis

ConclusionOverall our results show a global increase in the prevalence of HLMuRSA and HLMuRMRSA among clinical S. aureus isolates over time. However, there was only a significant increase in the prevalence of MuRMRSA compared to the other categories of strains especially MuRSA. Since for decolonization of MSSA and MRSA in both patients and healthcare personnel, mupirocin is currently still the most effective antibiotic, a reduction of its effectiveness can provide a risk for invasive infection. Monitoring of mupirocin resistance development remains critical.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research