A modeling and simulation-based approach to dose justification for sarecycline

Background: Sarecycline is a novel tetracycline analogue under development for the oraltreatment of acne vulgaris. Pharmacokinetic [PK] sampling was included in the phase 3 efficacy and safety studies to enable pharmacometric analyses in support of dose justification.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research