Microarray analysis to identify genes associated with a high-risk of metastasis in cutaneous squamous cell carcinoma tumors

Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer after basal cell carcinoma. While most cases are cured by excision, a substantial number of patients will develop local, regional, or distant recurrences, with the number of cSCC-related deaths approaching that from melanoma. Several clinical decisions, including the extent of surgical margins, the use of adjuvant radiation or chemotherapy, and sentinel lymph node biopsy/completion dissection, could be informed by a patient ’s relative risk of recurrence.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research