Risk factors predisposing patients to recurrence of calciphylaxis

Background: Calciphylaxis is a rare and potentially fatal disorder characterized by widespread cutaneous necrosis secondary to calcium deposition within small- and medium-sized vessels and subsequent thrombosis. Patients with comorbid end-stage renal disease, hyperparathyroidism, diabetes, and warfarin use are at increased risk of developing this disease. While complete resolution of lesions has increasingly been reported, some patients go on to develop recurrent disease. There remains a paucity of literature exploring risk factors which predispose patients to recurrence of calciphylaxis.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research