Short contact 5-fluorouracil with zinc oxide occlusive dressing and cryotherapy for field and focal treatment of actinic keratoses – Adjunct to excision of upper extremity squamous cell carcinomas in organ transplant recipients

Introduction: Topical 5-Fluorouracil (5-FU) under zinc oxide occlusion has been reported to be effective in reducing actinic damage and as an adjuvant to surgery for squamous cell carcinomas (SCCs) on diffusely photodamaged skin. It has also been shown to increase patient satisfaction as well as compliance and is tolerable without major side effects. Organ transplant patients are at an increased risk of developing skin cancer due to immunosuppressive medications. 5-FU is frequently prescribed as an at-home field treatment for diffuse actinic keratoses (AKs).
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research