Three-dimensional histology surgery in dermatofibrosarcoma protuberans: A case series

Dermatofibroma protuberans (DFSP) is an uncommon, locally aggressive cutaneous soft tissue sarcoma of low-intermediate malignancy that favors young adults. It usually presents as an asymptomatic, indurated, skin-colored plaque that enlarges over a period of months to years. Histologically, it is characterized by its capacity to infiltrate the dermis and subcutaneous tissue in the form of peripheral tentacle-like projections. This feature justifies a high rate of local recurrence, while the rate of metastasis remains low.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research