Folliculotrophic mycosis fungoides in a pediatric patient and review of current prognostic guidelines

Folliculotrophic mycosis fungoides (MF) is an aggressive variant of cutaneous T-cell lymphoma that typically appears on the head and neck in adults and historically was thought to have a worse prognosis than other forms of MF. Folliculotrophic MF used to be staged via the tumor-node-metastasis system, but these stages did not correlate with clinically meaningful prognosis information. Recently, a large prospective cohort study found that cases of folliculotrophic MF can be subdivided into indolent vs aggressive forms based on their histopathological appearance, with those tumors that looked like early plaque stage pathologically having survival rates similar to patch stage MF and those with advanced-stage plaques on pathology having similar survival rates to tumor stage MF.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research