Paradoxical psoriasiform reactions by anti-TNF treated with Ustekinumab in patients with inflammatory bowel disease

Introduction: Paradoxical psoriasiform reactions due to the use of anti-TNF form a clinical spectrum that requires a correct multidisciplinary approach. This is due to the fact that they often cause great functional impotence, especially palmoplantar pustulosis or severe forms of the scalp, being refractory to the treatments classically used. Ustekinumab, following its recent approval for the treatment of inflammatory bowel disease (IBD), may be a good therapeutic alternative for these patients.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research