LB1098 Placebo response in itch and atopic dermatitis studies

Introduction: The purpose of this study was to assess whether the improvements in itch seen with placebo are due to the use of minimum itch scores as an entry criterion. Methods: A systematic literature review was performed using MEDLINE to find studies that reported the effect of placebo on itch. We then characterized these studies based on whether or not itch was an entry criterion. Itch outcome in placebo arms of studies, quantified using visual analog scale (VAS), was gathered and compared to each other.

Source: Journal of Investigative Dermatology - August 21, 2019 Category: Dermatology Authors: W. Haidari, E. Quan, C. Patel, L.C. Strowd, S.R. Feldman Tags: Interventional Studies, Clinical and Patient Reported Outcomes Source Type: research