LB1137 Huiyang Shengji Extract enhances diabetic wound healing of db/db mouse by promoting angiogenesis and macrophage polarization

This study aims to investigate the effect and molecular mechanism of HSE on wound healing of diabetic mice. Diabetic db/db mice were operated with full-thickness excision, with wound treated externally by HSE. The results showed that HSE reduces the wound area on days 7 and 14; Compared with the model group on day 10, the local blood flow of the wound of HSE group was significantly increased according to Doppler ultrasound imaging.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Tissue Regeneration and Wound Healing Source Type: research