PD ‐L1 expression, CD8+ and CD4+ lymphocyte rate are predictive of pathological complete response after neoadjuvant chemoradiotherapy for squamous cell cancer of the thoracic esophagus
ConclusionsPD ‐L1 expression and CD8+ and CD4+ lymphocyte rate were predictive of ypCR after neoadjuvant CTRT for SCC of the thoracic esophagus with adequate accuracy. Furthermore, recurrence/relapse was associated with high level of CD4+ T cell infiltration. However, the small sample size prevented to draw def initive conclusions; further studies are necessary to evaluate the prognostic role of these markers.
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Matteo Fassan,
Francesco Cavallin,
Vincenza Guzzardo,
Andromachi Kotsafti,
Melania Scarpa,
Matteo Cagol,
Vanna Chiarion ‐Sileni,
Luca Maria Saadeh,
Rita Alfieri,
Ignazio Castagliuolo,
Massimo Rugge,
Carlo Castoro,
Marco Scarpa Tags: ORIGINAL RESEARCH Source Type: research