Midkine Is Elevated After Multiple Trauma and Acts Directly on Human Cardiomyocytes by Altering Their Functionality and Metabolism
Conclusion and Implications: Midkine is elevated in human and porcine plasma after multiple trauma, affecting the functionality and metabolism of human cardiomyocytes in vitro. If the application of CytoSorb300 filtration for patients after multiple trauma is a promising therapeutic approach to prevent post-traumatic cardiac dysfunction requires further examination.
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
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