Spectroscopic measurement of 5-ALA-induced intracellular protoporphyrin IX in pediatric brain tumors

ConclusionWe demonstrate a strong association between intraoperative observations and spectrometric measurements of PPIX fluorescence in tumor tissue. As in former studies, fluorescence signal was more commonly observed in malignant glial tumors. Further prospective controlled trials should be conducted to investigate the feasibility of 5-ALA-guided resection of pediatric brain tumors.
Source: Acta Neurochirurgica - Category: Neurosurgery Source Type: research