β Cell Senescence as a Common Contributor to Type 1 and Type 2 Diabetes.

β Cell Senescence as a Common Contributor to Type 1 and Type 2 Diabetes. Trends Mol Med. 2019 Aug 15;: Authors: Tian Y, Zhang Y, Fu X Abstract Type 1 (T1D) and type 2 diabetes (T2D), two distinct clinical entities principally driven by autoimmunity and metabolic dysfunction, respectively, are associated with β cell failure. Two studies (Thompson et al., Cell Metab., 2019 and Aguayo-Mazzucato et al., Cell Metab., 2019) now reveal a role for β cell senescence in T1D and T2D, and highlight the potential of senolytic therapy for these diseases. PMID: 31422036 [PubMed - as supplied by publisher]
Source: Trends in Molecular Medicine - Category: Molecular Biology Authors: Tags: Trends Mol Med Source Type: research