First-in-human study of TK-positive oncolytic vaccinia virus delivered by adipose stromal vascular fraction cells

ACAM2000, a thymidine kinase (TK)-positive strain of vaccinia virus, is the current smallpox vaccine in the US. Preclinical testing demonstrated potent oncolytic activity of ACAM2000 against several tumor type...
Source: Journal of Translational Medicine - Category: Research Authors: Tags: Research Source Type: research