NUQA: Estimating cancer spatial and temporal heterogeneity and evolution through alignment-free methods.
CONCLUSION: We hypothesise that this approach has the potential to reveal novel information about the heterogeneity and evolutionary trajectory of spatiotemporal tumour samples, potentially revealing early events in tumorigenesis and the origins of metastases and recurrences.
PMID: 31424551 [PubMed - as supplied by publisher]
Source: Mol Biol Cell - Category: Molecular Biology Authors: Roddy AC, Jurek A, Souza J, Gilmore A, O'Reilly PG, Stupnikov A, de Castro DG, Prise KM, Salto-Tellez M, McArt DG Tags: Mol Biol Evol Source Type: research
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