Therapy Options for Infants with Congenital Cytomegalovirus Infection - Implications for Setting Up Neonatal Screening Programs.

CONCLUSIONS: Antiviral treatment of neonates with congenital CMV infection and few symptoms including isolated hearing loss remains controversial. A generally accepted therapy, however, is pivotal before introducing universal or targeted screening for congenital CMV infection. PMID: 31426118 [PubMed - as supplied by publisher]
Source: Zeitschrift fur Geburtshilfe und Neonatologie - Category: Perinatology & Neonatology Authors: Tags: Z Geburtshilfe Neonatol Source Type: research

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Publication date: Available online 21 September 2019Source: Food Quality and PreferenceAuthor(s): Christina Hartmann, Michael SiegristAbstractThe enjoyment of meat and simultaneous disapproval of hurting animals create an ambivalent relationship with meat consumption. Meat-eating justification strategies are a means of coping with such cognitive dissonance. We aimed to determine whether the use of such justification strategies to defend meat consumption is linked to the moral evaluation of diverse free-range, wild and conventional meat production systems (e.g. free-range chicken, wild fish and veal from conventional produc...
Source: Food Quality and Preference - Category: Food Science Source Type: research
Publication date: Available online 21 September 2019Source: Chinese Chemical LettersAuthor(s): Rui Guo, Tianming Lv, Fengying Han, Zilin Hou, Guodong Yao, Bin Lin, Xiaobo Wang, Xiaoxiao Huang, Shaojiang SongABSTRACT(±)-Crataegusnorin A (1a/1b) and B (2a/2b), two pairs of rare 8,9′-epoxy-type norlignan enantiomers featuring a γ-butyrolactone ring, were isolated from the fruit of Crataegus pinnatifida. Their structures were determined via extensive spectroscopic analyses. Gauge-independent atomic orbital (GIAO) NMR chemical shift calculations, combined with the advanced statistical method DP4+ were employe...
Source: Chinese Chemical Letters - Category: Chemistry Source Type: research
Discussion of Developmental Effects on Aging Microtubule Function and Longevity in Nematodes Quantifying the Correlation Between Poverty and Faster Pace of Aging Matthew O'Connor Presenting on Underdog Pharmaceuticals at Undoing Aging 2019 Here Matthew O'Connor of the SENS Research Foundation talks about the research that led to founding of Underdog Pharmaceuticals, a biotech startup incubated by the foundation to commercialize a means of targeting 7-ketocholesterol in atheroscleros...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
CONCLUSION: Clinical and public health guidelines have a role to play in promoting health equity by explicitly considering equity in the process of guideline development. PMID: 31537503 [PubMed - as supplied by publisher]
Source: Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen - Category: Health Management Tags: Z Evid Fortbild Qual Gesundhwes Source Type: research
Publication date: Available online 20 September 2019Source: Social NetworksAuthor(s): Travis G. Tatum, Thomas U. GrundAbstractPrevious research on bullying implicitly assumes that individuals agree on who bullies whom and whom is bullied by who. We analyse dual-perspective networks from 96 school-classes in Germany, where adolescents were asked both whom they bully (confession network) and who bullies them (accusation network). Drawing from goal framing theory we explicitly examine discrepancies in the subjective perception of bullying, demonstrating that the majority of accusations have no corresponding confessions, and v...
Source: Social Networks - Category: Psychiatry & Psychology Source Type: research
[Mediation of data literacy in curricular education in otorhinolaryngology: watch and wait or anticipatory obedience?] HNO. 2019 Sep 19;: Authors: Offergeld C, Neudert M, Emerich M, Schmidt T, Kuhn S, Giesler M Abstract A comprehensive societal change is currently taking place, which also includes the medical field. The often heard "digital transformation" is also fundamentally transforming the health care system familiar to us, including the medical schools. While the Masterplan 2020 includes changes in the medical school structure and in the curricular content, it unfortunately focuses...
Source: HNO - Category: ENT & OMF Tags: HNO Source Type: research
CONCLUSION: The results demonstrated the nationwide acceptance of the ORL logbook by lecturers and students. The amount of critical learning targets which will have to be changed is moderate. This evaluation confirmed the relevance and balance of the ORL logbook content in the practical year training and the possibility of use independent of the location of ORL departments. PMID: 31538214 [PubMed - as supplied by publisher]
Source: HNO - Category: ENT & OMF Tags: HNO Source Type: research
Conclusions: For an appropriate approach to LGBTI-centered health care and health promotion, health professionals will need to adopt a better understanding of specific soft and hard skills.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
ian Klöhn Prion diseases are fatal neurodegenerative diseases that affect humans and animals. Prion strains, conformational variants of misfolded prion proteins, are associated with distinct clinical and pathological phenotypes. Host-strain interactions result in the selective damage of distinct brain areas and they are responsible for strain selection and/or adaptation, but the underlying molecular mechanisms are unknown. Prion strains can be distinguished by their cell tropism in vivo and in vitro, which suggests that susceptibility to distinct prion strains is determined by cellular factors. The neuroblastoma c...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
ConclusionTaken together, this study clearly demonstrated that the anti-Fenton activity of DFO inhibited apoptosis and caused blockade in ALP or autophagy dysfunction in SH-SY5Y cell lines. These outcomes further suggest that DFO provides neuroprotection by inhibiting apoptosis and inducing the progression of Autophagy- lysosomal pathway (ALP).Graphical abstract
Source: Journal of Trace Elements in Medicine and Biology - Category: Biochemistry Source Type: research
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