Hypersensitivity reactions to measles-mumps-rubella vaccine in patients with IgE-mediated cow's milk allergy

Publication date: Available online 15 July 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Mervin Piñones, Maria Landaeta, Paula Bustos, Paola Toche, Pamela Morales, Carola Escobar, Arturo Borzutzky, Rodrigo Hoyos-Bachiloglu
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research

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The Measles virus (MeV) and Mumps virus (MuV) are highly contagious paramyxoviruses that can be transmitted by respiratory droplets from or on direct contact with an infected person. The resulting diseases can lead to serious complications or death among children. The existing vaccines for MeV and MuV are live attenuated virus vaccines which are administered in two subcutaneous doses at 1 year of age and as early as one month later. Two doses of a combination measles, mumps and rubella vaccine are 97% effective against measles and 88% against mumps. A single dose of a combination measles, mumps, and rubella vaccine is 93% ...
Source: NIH OTT Licensing Opportunities - Category: Research Authors: Source Type: research
Source: Indian Journal of Pediatrics - Category: Pediatrics Source Type: research
Purpose of review Studying primary immunodeficiencies (PIDs) provides insights into human antiviral immunity in the natural infectious environment. This review describes new PIDs with genetic defects that impair innate antiviral responses. Recent findings New genetic defects in the interferon (IFN) signaling pathway include IFNAR1 deficiency, which causes uncontrolled infections with measles-mumps-rubella or yellow fever vaccines, and possibly also cytomegalovirus (CMV); and IRF9 deficiency, which results in influenza virus susceptibility. Genetic defects in several pattern recognition receptors include MDA5 deficienc...
Source: Current Opinion in Pediatrics - Category: Pediatrics Tags: ALLERGY, IMMUNOLOGY AND RELATED DISORDERS: Edited by Jordan S. Orange Source Type: research
AbstractObjectivesTo determine the allergic reactions that develop after Measles and Measles-Mumps-Rubella (MMR) vaccination, and whether any delay in the timing of vaccination occurs in children with food allergy.MethodsChildren with food allergy who were admitted to the Şişli Hamidiye Etfal Training and Research Hospital Healthy Child Clinic between 1st January 2015 and 30th June 2018 for Measles or MMR vaccination were studied retrospectively. Their age, delayed days of vaccination, the types of allergic food, the results of the specific IgE and skin tests, and any reaction after the vaccination were recorded.ResultsD...
Source: Indian Journal of Pediatrics - Category: Pediatrics Source Type: research
Source: Indian Journal of Pediatrics - Category: Pediatrics Source Type: research
Publication date: Available online 15 July 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Mervin Piñones, Maria Landaeta, Paula Bustos, Paola Toche, Pamela Morales, Carola Escobar, Arturo Borzutzky, Rodrigo Hoyos-Bachiloglu
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
(CNN) — There have been 971 cases of measles reported in the United States this year, the US Centers for Disease Control and Prevention said Thursday. This means 2019, which is not quite half over, now has the greatest number of cases in a single year in nearly three decades. The number of cases in 1994 was 963, which was lower than in 1992 when there were 2,237 cases. “Measles is preventable and the way to end this outbreak is to ensure that all children and adults who can get vaccinated, do get vaccinated. Again, I want to reassure parents that vaccines are safe, they do not cause autism. The greater danger i...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News CNN Measles Source Type: news
Unvaccinated individuals have been the focus of attention during this year’s measles outbreaks. A record 704 cases of the illness have been confirmed in 22 states so far in 2019, and the CDC says the majority of those diagnoses have been in unvaccinated people. Health officials have repeatedly warned nearly everyone to get the shot if they haven’t already — sometimes threatening fines for those who refuse. “Over 90% of the measles cases that have occurred in the U.S. have occurred in unvaccinated persons,” says Dr. William Schaffner, a professor of preventive medicine and infectious diseases a...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized public health Source Type: news
Nicolaas G. van der Maas, Dagmar Berghuis, Mirjam van der Burg and Arjan C. Lankester* Willem-Alexander Children's Hospital, Department of Pediatrics and Laboratory for Pediatric Immunology, Leiden University Medical Center, Leiden, Netherlands B cell reconstitution after hematopoietic stem cell transplantation (HSCT) is variable and influenced by different patient, donor, and treatment related factors. In this review we describe B cell reconstitution after pediatric allogeneic HST, including the kinetics of reconstitution of the different B cell subsets and the development of the B cell repertoire, and d...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
The Ohio teenager who made headlines for getting vaccinated against his mother’s wishes told the Senate on Tuesday that spreading vaccine misinformation is dangerous — but urged the public not to vilify those who do so. “Approaching this issue with the concern of education and addressing misinformation properly can cause change, as it did for me,” 18-year-old Ethan Lindenberger said while testifying before the Senate Health, Education, Labor and Pensions Committee on Tuesday. “Although the debate around vaccines is not necessarily centered around information, and concerns for health and sa...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized healthytime onetime vaccines Source Type: news
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