Immunoinflammatory responses to febrile lower respiratory infections in infants display uniquely complex/intense transcriptomic profiles

Febrile lower respiratory infections trigger uniquely potent/complex immunoinflammatory responses in infants, which enhance both immune maturation and asthma development. Characterization of underlying fever-associated transcriptomic profiles may unmask previously hidden clues regarding mechanisms driving asthma initiation.

Source: Journal of Allergy and Clinical Immunology - August 18, 2019 Category: Allergy & Immunology Authors: Anya C. Jones, Denise Anderson, Sally Galbraith, Emmanuelle Fantino, Diana Gutierrez Cardenas, James F. Read, Michael Serralha, Barbara J. Holt, Deborah H. Strickland, Peter D. Sly, Anthony Bosco, Patrick G. Holt Source Type: research