Cell surface clicking of antibody-recruiting polymers to metabolically azide-labeled cancer cells
Chem. Commun., 2019, Accepted Manuscript DOI: 10.1039/C9CC03379C, CommunicationAnnemiek Uvyn, Ruben De Coen, Olivier De Wever, Kim Deswarte, Bart Lambrecht, Bruno De Geest Triggering antibody-mediated innate immune mechanisms to kill cancer cells is an attractive therapeutic avenue. In this context, recruitment of endogenous antibodies to the cancer cell surface could be a viable... The content of this RSS Feed (c) The Royal Society of Chemistry
Publication date: Available online 17 September 2019Source: Microbial PathogenesisAuthor(s): Azar Najafi, Mohammad Reza Chaechi Nosrati, Ezatollah Ghasemi, Zahra Navi, Ali Yousefi, Hamidreza Majidiani, Hori Ghaneialvar, Kourosh Sayehmiri, Ma De la Luz Galvan-Ramirez, Mahdi FakharAbstractWe performed a systematic review and meta-analysis to reveal the association between Trichomonas vaginalis (TV) infection and the risk of prostate cancer (PCa) development. Systematic searching (PubMed/Medline, Scopus, Embase, Web of Science, Cinhal, Wiley, Cochrane, Psychoinfo, ProQuest and Google Scholar) was done, up to March 2018 for ca...
Conclusions: Adding albumin to early standard resuscitation with lactated Ringer’s in cancer patients with sepsis did not improve 7-day survival.
No abstract available
Objective: Cancer and its treatment are known to be important risk factors for sepsis, contributing to an estimated 12% of U.S. sepsis admissions in the 1990s. However, cancer treatment has evolved markedly over the past 2 decades. We sought to examine how cancer-related sepsis differs from non–cancer-related sepsis. Design: Observational cohort. Setting: National Readmissions Database (2013–2014), containing all-payer claims for 49% of U.S. population. Patients: A total of 1,104,363 sepsis hospitalizations. Interventions: We identified sepsis hospitalizations in the U.S. National Readmissions Dat...
Conclusions: The results suggest that these polymorphisms probably has not a substantial role in Iranian CRC risk and is not a serious potential factor in risk assessment of mentioned disease among Iranians. PMID: 31523666 [PubMed]
ConclusionsDecrease in the rates of perioperative outcomes parallels improvements in patient selection and perioperative management of early-stage NSCLC resection patients. Predictors of pulmonary complication could be used to improve selection criteria for surgery and to reduce the incidence of pulmonary complication in these patients.
This study investigated the effects of miR-146a on CSCs' tumorigenesis and invasion. Tumorsphere cells (TCs) were enriched from the HeLa cell line. Real-time PCR, Western blots, ALDH assays, colony formation and invasion assays, luciferase reporter assays and the Xenograft mouse model were used to determine the underlying mechanism of CC. The results showed that TCs displayed higher ALDH activity and miR-146a was upregulated in differentiated TCs. Moreover, miR-146a inhibitor increased colony formation and cell invasion in TCs while miR-146a mimics displayed the opposite roles. An inverse relationship between miR-146a and ...
A cancer-causing compound banned by U.S. regulators last year as a food additive has been found at potentially dangerous levels in mint and menthol flavored e-cigarette liquids and smokeless tobacco products, researchers said on Monday.Reuters Health Information