Impact of non-uniform attenuation correction in a dynamic [ 18 F]-FDOPA brain PET/MRI study

ConclusionsPET kinetic analyses based on a reference region are especially sensitive to the non-uniform bias in PET quantification from AC inaccuracies in brain PET/MRI. Depending on the position of the reference region and the bias with respect to the analysed region, kinetic analyses suffer different levels of bias. Considering bone in the μ-map can potentially result in larger errors, compared to the absence of bone, when non-uniformities in PET quantification are introduced.

http://link.springer.com/10.1186/s13550-019-0547-0

Source: EJNMMI Research - August 18, 2019 Category: Radiology Source Type: research